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Clinical trials and research at Ain Shams University

• 147Clinical trials
• 6New in 30 days
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Newest trials

All recruiting trials (147)

• NAVA use in preterm neonates with respiratory distress syndrome

  This trial tests whether neurally adjusted ventilatory assist (NAVA) helps preterm babies with respiratory distress syndrome breathe more easily than conventional ventilation.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07926009

• Ruta C and Vitamin C in Sepsis: Adding antioxidants to standard care

  This trial tests whether adding Ruta C (rutin plus vitamin C) or vitamin C alone to standard sepsis treatment helps adults in the ICU stay shorter and recover better.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07922213

• Left DLPFC rTMS vs iTBS for emotional dysregulation, impulsivity, and NSSI in Borderline Personality Disorder

  This trial tests whether high-frequency rTMS or intermittent theta-burst stimulation over the left DLPFC can help reduce emotional instability, impulsivity, and non-suicidal self-injury in adults with Borderline Personality Disorder.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07919587

• Trimetazidine as an extra therapy for aluminum phosphide poisoning

  In this pilot trial, adults with acute aluminum phosphide poisoning receive standard care plus trimetazidine to see if it helps save lives and improve recovery.

  Recruiting Phase 3 Ain Shams University · Cairo, Abbassia · NCT07916922

• Comparing 3D Face Scans with Manual Measurements for Vertical Dimension in People with Complete Dentures

  This study tests whether a 3D face scan can reliably measure the vertical dimension of occlusion in people who wear complete dentures, compared with traditional manual methods.

  Recruiting at 2 sites Ain Shams University · Cairo, Nasr City and 1 other locations · NCT07898332

• Pre-adapted 3D-printed, patient-specific mesh for unilateral orbital fractures with or without navigation

  This study tests whether pre-bending an in-stock titanium mesh using a patient’s 3D-printed skull model improves repair outcomes for unilateral orbital fractures compared with conventional free-hand bending and with navigation-assisted placement.

  Recruiting Ain Shams University · Cairo, Abbasia and 1 other locations · NCT07882121

• Papillary vs non-papillary access during PCNL

  This trial tests whether non-papillary renal access is a safe and effective alternative to the standard papillary approach during percutaneous nephrolithotomy in adults with kidney stones.

  Recruiting Ain Shams University · Cairo · NCT07855354

• Low-Volume PENG Block With Dexamethasone After Hip Replacement

  This trial tests whether a smaller PENG block with dexamethasone provides similar pain relief but preserves quadriceps strength after hip replacement, compared with the standard-volume PENG block.

  Recruiting Phase 4 Ain Shams University · Cairo, Cairo Governorate · NCT07855341

• Melatonin plus inhaled nitric oxide for pulmonary hypertension in full-term newborns

  This study tests whether adding melatonin to inhaled nitric oxide helps treat pulmonary hypertension in full-term neonates.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07850934

• See if high-dose vitamin D helps bed sores heal in ICU patients

  This study tests whether giving a high-dose vitamin D supplement helps bed sores heal faster in critically ill ICU patients who are deficient in vitamin D.

  Recruiting Ain Shams University · Cairo · NCT07813975

• Oral verapamil in newly diagnosed children and teens with type 1 diabetes

  This study tests whether taking verapamil by mouth can help preserve pancreatic beta cells and reduce insulin needs in kids and teens with recently diagnosed type 1 diabetes.

  Recruiting Phase 2/3 Ain Shams University · Cairo · NCT07804849

• Magnesium given during colorectal cancer surgery to see if it lowers inflammation afterward

  We’re testing whether giving magnesium sulfate during open colorectal cancer surgery can reduce postoperative inflammation in patients.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07803601

• Sickle cell disease registry at Ain Shams University

  This project creates an Ain Shams University registry of children and young people with sickle cell disease to track their health over time without providing a treatment.

  Recruiting Ain Shams University · Cairo and 1 other locations · NCT07800247

• National Egyptian HLH Registry for pediatric patients

  A national HLH registry is being created in Egypt to collect information about pediatric HLH patients to improve understanding and care.

  Recruiting Ain Shams University · Cairo and 1 other locations · NCT07800234

• Multimodal regional nerve blocks to improve recovery after off-pump CABG

  This study tests whether using multiple regional nerve blocks can reduce pain and help patients recover after off-pump coronary artery bypass surgery.

  Recruiting Ain Shams University · Cairo · NCT07794527

• Trimetazidine to help diabetic neuropathy symptoms and endothelin-1 levels

  This study tests whether taking trimetazidine can improve symptoms for adults with type 2 diabetes and diabetic peripheral neuropathy.

  Recruiting Phase 1/2 Ain Shams University · Cairo · NCT07794475

• L-Carnitine as an add-on for healing diabetic foot ulcers

  This study tests whether taking L-Carnitine helps wound healing in adults with diabetic foot ulcers, alongside standard diabetes and wound care.

  Recruiting Phase 2 Ain Shams University · Cairo, Cairo Governorate and 1 other locations · NCT07768228

• Lactoferrin Supplement in Diabetic Kidney Disease

  Scientists test whether adding lactoferrin helps people with diabetic nephropathy who also have moderately to severely increased urinary albumin.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT07764991

• Flexible Ureteroscopy With Navigable Suction vs Mini-PCNL in Kids with Kidney Stones

  This study tests whether flexible ureteroscopy with suction helps treat kidney stones in children compared with mini-percutaneous nephrolithotomy.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07763743

• Iliac vein stenting with dedicated venous stents for chronic post-thrombotic venous ulcers

  This study tests whether using dedicated iliac venous stents to reopen obstructed veins helps heal chronic leg ulcers caused by post-thrombotic syndrome in adults.

  Recruiting Ain Shams University · Cairo · NCT07762222

• Red Cell Distribution Width to Albumin Ratio in Burn Patients

  This observational study tests whether the ratio of red cell distribution width to albumin measured within 24 hours of admission can predict 30-day mortality in adults with burn injuries.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07761845

• LIFT vs Cyanoacrylate Glue in High Transsphincteric Perianal Fistula

  This trial tests whether tying the fistula tract (LIFT) or using cyanoacrylate glue works better for healing in adults with a high transsphincteric perianal fistula.

  Recruiting Ain Shams University · Cairo · NCT07744672

• Protective role of alpha-lipoic acid in chemotherapy-induced mucositis for colorectal cancer

  This trial tests whether taking alpha-lipoic acid can reduce mouth sores caused by 5-FU chemotherapy in adults with colorectal cancer.

  Recruiting Phase 2/3 Ain Shams University · Cairo · NCT07736495

• Long-term follow up after transvaginal cystocele repair with four-armed collagen-coated mesh

  This study tests whether a four-armed collagen-coated polyester mesh used in transvaginal cystocele repair remains safe and effective more than five years after surgery in women who had the procedure.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07730749

• Nicorandil for rheumatoid arthritis: a two-phase study comparing it to placebo

  This trial tests whether nicorandil twice daily for 3 months can reduce rheumatoid arthritis symptoms compared with a placebo.

  Recruiting Phase 2/3 Ain Shams University · Cairo, Abbasia · NCT07730723

• Tamsulosin alone vs. tamsulosin with tadalafil for troublesome urinary symptoms from enlarged prostate

  This study tests whether adding tadalafil to tamsulosin helps men with BPH see better urinary symptoms and quality of life, using two tadalafil doses over 12 weeks.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07722884

• Simultaneous Integrated Boost Radiotherapy for High- and Very High-Risk Prostate Cancer

  This study tests a hypofractionated SIB-VMAT radiotherapy approach to see if it safely treats the prostate and pelvic lymph nodes in high-risk prostate cancer patients over 20 fractions.

  Recruiting at 3 sites Phase 2 Ain Shams University · Cairo and 2 other locations · NCT07693075

• Internal Jugular Vein Collapsibility to Predict Hypotension in Older Adults Undergoing Laparoscopic Colorectal Surgery

  This study tests whether measuring the internal jugular vein collapsibility index can predict intraoperative hypotension in patients aged 60 and older undergoing elective laparoscopic colorectal surgery.

  Recruiting Ain Shams University · Cairo · NCT07692425

• Empagliflozin for Pediatric Heart Failure

  This study tests whether empagliflozin added to standard care helps children with heart failure.

  Recruiting Phase 2 Ain Shams University · Cairo, Cairo Governorate · NCT07692256

• Hip fracture: PENG block alone vs PENG with LFCN block for easing spinal anesthesia positioning

  This study tests whether adding an LFCN block to the PENG block helps patients with hip fractures lie still for spinal anesthesia better than the PENG block alone.

  Recruiting Ain Shams University · Cairo · NCT07687290

• Nd:YAG Laser Plus Sclerotherapy vs Diode Laser Plus Sclerotherapy for Spider Veins and Reticular Veins

  This study tests whether Nd:YAG laser combined with injection sclerotherapy clears reticular veins and spider veins better than a diode laser combined with injection sclerotherapy using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) approach.

  Recruiting Ain Shams University · Cairo · NCT07678697

• Ketamine-Propofol vs Dexmedetomidine-Propofol Sedation for Pediatric Cardiac Catheterization

  This study tests two sedative combinations to see which is safer and more effective for children 2–12 undergoing device closure of simple left-to-right heart shunts.

  Recruiting Phase 1 Ain Shams University · Cairo · NCT07669012

• Impact of a Parasternal Intercostal Block on Internal Thoracic Artery Harvest in CABG

  This study tests whether a superficial parasternal intercostal plane block can improve the ITA caliber and help surgeons harvest the graft during CABG.

  Recruiting Phase 3 Ain Shams University · Cairo, Cairo Governorate · NCT07663435

• Different intracanal medicines for retreatment of lower first molars

  This study tests three intracanal medications to see which best reduces inflammation, heals lesions, and relieves pain in retreatment of a lower first molar with a periapical lesion.

  Recruiting Phase 1 Ain Shams University · Cairo · NCT07641933

• N-acetylcysteine for diabetic retinopathy in adults with type 2 diabetes

  This study tests whether taking N-acetylcysteine for three months can help people with type 2 diabetes who have mild to moderate diabetic retinopathy.

  Recruiting at 2 sites Phase 4 Ain Shams University · Cairo and 1 other locations · NCT07634991

• Closure of a macular hole with Tenon capsule graft versus ILM flap

  This pilot study tests whether using a piece of the patient’s Tenon capsule can help close a macular hole as well as or better than the standard ILM flap technique.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07633457

• Can ultrasound of parasternal intercostal muscles and the diaphragm help predict if a patient will be weaned from the ventilator

  This study tests whether ultrasound measurements of the diaphragm and parasternal intercostal muscles can help predict successful weaning from mechanical ventilation in adults in the ICU.

  Recruiting Ain Shams University · Cairo · NCT07630662

• Palmitoylethanolamide in Ulcerative Colitis

  This study tests whether taking palmitoylethanolamide helps people with active mild-to-moderate ulcerative colitis to improve symptoms and quality of life compared with a placebo.

  Recruiting Ain Shams University · Cairo, El-Abbasia · NCT07609810

• Pectopexy vs Sacrocolpopexy for apical prolapse: learning curve and effectiveness

  This study tests whether laparoscopic pectopexy works as well as laparoscopic sacrocolpopexy for apical prolapse and how quickly surgeons become proficient.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07596498

• How to size a child’s breathing tube using ultrasound versus age-based formulas

  This study tests whether ultrasound measurements of the throat can help pick the right endotracheal tube size for children with single-ventricle hearts, potentially reducing trouble after intubation.

  Recruiting Ain Shams University · Cairo, Abbasseya · NCT07586592

• Dexmedetomidine or ketamine added to bupivacaine for caudal pain relief in lumbosacral surgery

  This trial will test whether adding dexmedetomidine or ketamine to bupivacaine in a fluoroscopy-guided caudal block improves perioperative pain control for adults having lumbosacral surgery under general anesthesia.

  Recruiting Phase 3 Ain Shams University · Cairo · NCT07573969

• Tamsulosin 0.4 mg with Tadalafil 5 mg versus 2.5 mg to reduce symptoms from ureteral stents

  This will test whether adding Tadalafil at 5 mg or 2.5 mg to Tamsulosin 0.4 mg better reduces stent-related symptoms for adults with a double-J ureteral stent after stone removal.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07562282

• Carotid ultrasound versus heart echo to guide fluids in septic shock

  This study will test whether carotid artery Doppler flow or left ventricular end-diastolic measurements from echocardiography better predict which adults with septic shock will respond to a fluid bolus.

  Recruiting Ain Shams University · Cairo · NCT07550400

• Treatments to reduce interdental black triangles

  This trial will try three methods—surgical tube grafting, hyaluronic acid injections, and a composite injection-molding technique—to close or reduce interdental black triangles in adults with mild to moderate papilla loss.

  Recruiting Ain Shams University · Cairo · NCT07548203

• Midazolam‑Ketamine versus Dexmedetomidine to prevent emergence delirium after deep sedation in children with burns

  We will try whether a midazolam‑ketamine combination or dexmedetomidine better prevents emergence delirium in children aged 3–16 undergoing deep sedation for burn dressing changes or minor procedures.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT07519863

• Costoclavicular versus lateral-sagittal infraclavicular block for hand and forearm surgery

  This study will see if the costoclavicular ultrasound-guided brachial plexus block produces a faster onset of numbness and motor block than the lateral-sagittal infraclavicular block in adults having hand or forearm surgery.

  Recruiting Ain Shams University · Cairo · NCT07517809

• Predicting survival in people with manifest tetanus using three severity scores.

  This project will test whether three scoring systems (Tetanus Severity Score, Dakar Score, and Philips Score) can help predict which adults with manifest tetanus will survive their hospital stay.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07512167

• Infraclavicular axillary vein collapsibility to predict who will respond to fluids in sepsis

  This trial tests whether the infraclavicular axillary vein collapsibility index can tell which adults with sepsis who are breathing on their own will increase their blood flow after getting IV fluids.

  Recruiting Ain Shams University · Cairo · NCT07507877

• Anti‑Factor Xa–guided enoxaparin dosing for preventing blood clots in adults with major burns

  This trial will test whether using anti‑Factor Xa blood levels to guide enoxaparin dosing prevents venous blood clots better than standard weight‑based dosing in adults with moderate-to-large thermal burns.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07464808

• High-level laser therapy for oral mucositis in children receiving hematopoietic stem cell transplant

  This trial tests whether high-level laser therapy can reduce the pain and severity of oral mucositis in children undergoing hematopoietic stem cell (bone marrow) transplantation.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07436650

• Rezum versus prostatic artery embolization for relieving urinary symptoms from BPH

  This study will test whether Rezum (water vapor therapy) or prostatic artery embolization works better at reducing bothersome urinary symptoms in men with moderate-to-severe BPH.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07416227

• 3D-printed versus conventional Hyrax expanders to widen the upper jaw in adolescents

  This compares a 3D-printed Hyrax expander with a conventional Hyrax to see which widens the upper jaw better in adolescents with maxillary transverse deficiency.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07411092

• Pre-op ultrasound of the IVC and aorta to predict blood pressure drops after anesthesia

  We will see if simple pre-op ultrasound measurements of the IVC collapsibility and the caval–aorta index can predict which adults having elective craniotomy will have a drop in blood pressure when general anesthesia is started.

  Recruiting Ain Shams University · Cairo · NCT07399093

• Systematic treatment approach for children with orbital lymphatic malformation using sirolimus

  This will test whether sirolimus, given alone or with injection sclerotherapy, is safe and helps children and teens (ages 1–18) with orbital lymphatic malformation.

  Recruiting Phase 3 Ain Shams University · Cairo, Cairo Governorate · NCT07378657

• Comparing three single-use flexible ureteroscopes for treating kidney stones

  This compares three single-use flexible ureteroscopes to see which gives the best results for adults aged 18–60 with kidney stones smaller than 20 mm.

  Recruiting Ain Shams University · Cairo · NCT07360353

• Comparing two ultrasound-guided chest nerve blocks for pain control after VATS

  This test compares an erector spinae plane block and a serratus anterior plane block to see which gives better pain relief for adults having video-assisted thoracoscopic surgery (VATS).

  Recruiting Ain Shams University · Cairo, Abbassia-Egypt · NCT07360028

• Fixing large-angle outward eye turn with either muscle transplantation or Y-splitting recession

  This trial will try two types of monocular eye-muscle surgery—muscle transplantation and Y-splitting recession—in people over 6 with large-angle exotropia (50–70 prism diopters).

  Recruiting Ain Shams University · Cairo · NCT07350330

• Shorter-course external-beam radiotherapy with weekly chemotherapy and high-dose-rate brachytherapy for cervical cancer

  This tests whether a moderately shortened schedule of external radiotherapy given with weekly chemotherapy plus high-dose-rate brachytherapy helps people with stage IB–IIIC1 cervical cancer.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07343531

• PGE2 metabolite levels and development of significant patent ductus arteriosus in preterm infants

  This study will see if blood levels of a prostaglandin E2 metabolite predict which preterm babies (≤32 weeks) develop a hemodynamically significant patent ductus arteriosus.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07338370

• Stepwise enteral feeding plan to improve nutrition for critically ill children in the PICU.

  This will try a step-by-step tube-feeding plan to see if it helps critically ill infants and children in the pediatric ICU get the nutrition they need.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07307027

• Mini‑PCNL versus flexible ureteroscopy with a suction sheath for 2–3 cm kidney stones

  This tests whether mini‑PCNL or flexible ureteroscopy with a suction sheath better clears 2–3 cm kidney stones and leads to fewer complications in adults.

  Recruiting Ain Shams University · Cairo · NCT07306819

• Silymarin versus hesperidin/diosmin for fibromyalgia symptom relief

  This project will test whether silymarin or a hesperidin/diosmin combination can ease symptoms in adults with fibromyalgia who continue to have pain despite conventional therapy.

  Recruiting Ain Shams University · Cairo · NCT07293767

• Dynamic navigation versus pre-made guides for placing upper-jaw dental implants

  This will test whether using a real-time dynamic navigation screen or a pre-made surgical guide gives more accurate implant placement for healthy adults missing an upper tooth.

  Recruiting Phase 4 Ain Shams University · Cairo · NCT07291336

• Alpha lipoic acid to prevent radiation skin reactions in women with breast cancer

  This trial will test whether taking alpha lipoic acid can prevent radiation-induced skin irritation in women receiving adjuvant radiotherapy for early-stage breast cancer.

  Recruiting Ain Shams University · Zagazig · NCT07256119

• Bite timing in lower overdentures supported by conventional versus mini dental implants

  This test will see if lower overdentures attached to two conventional implants or four mini-implants change bite contact and release times for people who have lost all lower teeth.

  Recruiting at 2 sites Ain Shams University · Cairo and 1 other locations · NCT07256106

• Nebivolol to protect the heart during trastuzumab treatment for HER2‑positive breast cancer

  This study will test whether taking nebivolol 5 mg can prevent drops in heart function in adults with newly diagnosed early or locally advanced HER2‑positive breast cancer who are starting trastuzumab.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT07233499

• Vitamin K2 to help prevent steroid-related bone loss in children with nephrotic syndrome

  This tests whether daily oral vitamin K2 can help prevent bone loss in children with nephrotic syndrome who have been on long-term glucocorticoids.

  Recruiting Ain Shams University · Cairo · NCT07206537

• Using blood cell ratios and procalcitonin to predict outcomes for adults with sepsis in the ICU

  This project will test whether routine blood measures—neutrophil-to-lymphocyte-and-platelet ratio, procalcitonin, and total white blood cell count—can help predict outcomes for adults with sepsis in the intensive care unit.

  Recruiting Ain Shams University · Cairo · NCT07200817

• Plasma D-dimer and severity in adult community-acquired pneumonia

  This project will see if higher blood D-dimer levels are linked to stronger inflammation and worse survival in adults with community-acquired pneumonia.

  Recruiting Ain Shams University · Cairo · NCT07199530

• Intranasal vs IV fentanyl for procedural pain in preterm newborns

  This trial will test whether a nasal spray or an intravenous dose of fentanyl works better to relieve short-term procedure pain in preterm newborns.

  Recruiting Early Phase 1 Ain Shams University · Cairo · NCT07190625

• Resilience training to reduce stress in nursing students

  This 10-week resilience training will test if nursing students can handle stress better.

  Recruiting Ain Shams University · Cairo, Cairo Governorate and 1 other locations · NCT07181603

• Isoflurane versus sevoflurane effects on oxidative stress during laparoscopic gallbladder removal

  This trial will test whether isoflurane or sevoflurane causes different levels of oxidative stress in adults having elective laparoscopic gallbladder removal.

  Recruiting Ain Shams University · Cairo · NCT07152912

• Does turning patients during doxycycline pleurodesis improve success and comfort for malignant pleural effusion?

  We will test whether turning people during doxycycline pleurodesis helps seal cancer-related pleural fluid and improves comfort.

  Recruiting Ain Shams University · Cairo · NCT07147270

• Self-assembling peptide versus CPP-ACP to reduce white spot lesions on front teeth

  This study will test whether a self-assembling peptide (Curodont Repair) or a CPP‑ACP varnish (MI Varnish) better improves the color and reduces the size of early white spot lesions in people aged 15–25 after orthodontic treatment.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07146464

• Linking genetic changes to symptoms in Egyptian children with congenital muscle disorders

  This project will test whether specific genetic changes explain symptoms in Egyptian children under 18 who have congenital myopathies or congenital muscular dystrophies.

  Recruiting Ain Shams University · Cairo · NCT07138963

• Carotid Doppler and echocardiography to predict fluid response in children with septic shock

  We will test whether carotid Doppler ultrasound and echocardiography can tell which children with septic shock will respond to fluid treatment.

  Recruiting Ain Shams University · Cairo · NCT07136532

• Neutrophil-to-lymphocyte ratio in COPD flare-ups.

  This project will test whether a routine blood measure called the neutrophil-to-lymphocyte ratio can help predict severity, outcomes, and treatment response in adults hospitalized with COPD flare-ups.

  Recruiting Ain Shams University · Cairo, Abbasyea · NCT07125352

• Lemongrass and lavender aromatherapy to reduce dental injection anxiety in children

  This test will see if inhaling lemongrass or lavender helps 7–11-year-old children feel less anxious and have less pain during dental injections.

  Recruiting Phase 4 Ain Shams University · Cairo, Cairo Governorate · NCT07113080

• Psychotropic medications and fall risk after hospital discharge in older adults

  This study will see if taking psychotropic medicines increases the chance of falls and related fractures in people aged 60 and older after they leave the geriatric hospital.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07112573

• Osseodensification forMol ar Septum Expansion in Immediate Molar Implants

  This study tests whether osseodensification helps place immediate molar implants more stably compared with traditional drilling, in adults needing extraction and replacement teeth.

  Recruiting Ain Shams University · Cairo and 1 other locations · NCT07108361

• Comparing a dental anesthesia injector versus the traditional syringe for numbing upper baby molars in children

  This trial tests whether a dental anesthesia injector causes less pain and anxiety than a regular syringe in 6–8-year-old children needing local anesthesia for pulpotomy.

  Recruiting at 2 sites Ain Shams University · Cairo, Cairo Governorate and 1 other locations · NCT07101068

• Zirconia-based composite customized healing abutments for healthier soft tissue around dental implants

  This test will compare zirconia-based composite customized healing abutments with conventional composite abutments to see if they help gum tissue heal better after delayed dental implant placement in adults missing a tooth.

  Recruiting Ain Shams University · Cairo, Abaseya · NCT07095881

• Sandwich total neoadjuvant treatment with short-course radiotherapy for stage II–III rectal cancer

  This trial tests whether giving chemotherapy both before and after short-course radiotherapy (a 'sandwich' approach) is effective and safe for people with stage II–III rectal cancer.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT07095439

• Comparison of neutrophil-to-lymphocyte ratio and lactate-to-albumin ratio as predictive inflammatory markers for sepsis

  This study will test whether the neutrophil-to-lymphocyte ratio or the lactate-to-albumin ratio better predicts outcomes for adults (18–80) with sepsis or septic shock from lower respiratory tract infections admitted to the ICU.

  Recruiting Ain Shams University · Cairo, Abbassia · NCT07089524

• Resveratrol added to usual treatment for moderate-to-high rheumatoid arthritis

  This will see if giving adults with moderate-to-high rheumatoid arthritis 1 g of resveratrol daily alongside their usual medicines for three months reduces inflammation, disease activity, and improves quality of life.

  Recruiting Ain Shams University · Cairo · NCT07089381

• Dexmedetomidine added to bupivacaine caudal block for children having open appendectomy.

  This trial will test whether adding dexmedetomidine to bupivacaine in a caudal block gives children longer and better pain relief and fewer emergence problems after open appendectomy.

  Recruiting Ain Shams University · Cairo · NCT07088900

• Using renal artery duplex ultrasound to check kidney blood flow in ICU patients with acute kidney injury

  We will test whether a bedside renal artery duplex ultrasound measurement (renal resistive index) can detect early changes in kidney blood flow in critically ill adults with acute kidney injury.

  Recruiting Ain Shams University · Cairo · NCT07073508

• HVGIC versus bulk‑fill composite for moderate Class II posterior cavities

  This study will test whether highly viscous glass ionomer or a bulk‑fill resin composite works better for moderate Class II cavities in adults who have at least two such lesions.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07067164

• Using AR and VR glasses to help children feel less pain and anxiety during local dental anesthesia

  This project will try augmented reality (AR) and virtual reality (VR) glasses to see if they help children aged 5–8 feel less pain and anxiety during local dental anesthesia.

  Recruiting Ain Shams University · Cairo, Egypt · NCT07060170

• Using blood inflammation markers (CRP, albumin, CAR, mGPS) to predict outcomes in diffuse large B‑cell lymphoma

  This project tests whether common blood inflammation markers (CRP, albumin, CRP-to-albumin ratio, and mGPS) can help predict how adults with newly diagnosed DLBCL will respond to standard R-CHOP chemotherapy and what side effects they may get.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07057765

• Electronic versus conventional dental syringes for reducing pain and anxiety during local anesthesia in children

  This test will see if electronic dental syringes cause less pain and anxiety than conventional syringes in children aged 6–8 during local anesthetic injections.

  Recruiting Ain Shams University · Cairo · NCT07045116

• Early progression of non-center diabetic macular edema after phacoemulsification

  This will see if non-center-involving diabetic macular edema worsens in the early weeks after cataract surgery in adults with diabetes.

  Recruiting Ain Shams University · Cairo · NCT07038967

• Melatonin for people with diabetic peripheral neuropathy

  This trial will test whether adding melatonin to usual care helps adults with type 2 diabetes who have peripheral neuropathy by reducing oxidative stress, lowering inflammation, and improving symptoms.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT07036796

• Oral NSAIDs plus paracetamol versus local dexamethasone infiltration for post-tonsillectomy pain in children

  This test will see if children aged 4–10 have less pain after tonsillectomy when given oral NSAIDs with paracetamol versus when dexamethasone is injected into the tonsil beds.

  Recruiting Ain Shams University · Cairo · NCT07035314

• Oral caffeine to reduce pain during acute migraine attacks

  This test will see if a single 200 mg oral caffeine tablet taken during an acute migraine can reduce pain for adults with episodic or chronic migraine with or without aura.

  Recruiting Phase 4 Ain Shams University · Cairo · NCT07022496

• Comparing two pain management techniques for patients undergoing VATS

  This study is testing which of two pain management techniques works better for people having video-assisted thoracoscopic surgery to help them recover with less pain and fewer opioids.

  Recruiting Ain Shams University · Cairo · NCT06996691

• Preventing low blood pressure after spinal anesthesia with a small dose of ketamine in orthopedic surgery

  This trial will test if a single sub‑anesthetic IV dose of ketamine given before spinal anesthesia can prevent low blood pressure in adults having elective orthopedic surgery.

  Recruiting Ain Shams University · Cairo · NCT06995690

• Comparing dexmedetomidine and bupivacaine for pain management after brain surgery

  This study is testing if adding dexmedetomidine to bupivacaine can help reduce pain better after brain surgery compared to using bupivacaine alone.

  Recruiting Ain Shams University · Cairo · NCT06993922

• Evaluating the effects of dapagliflozin on kidney function in advanced chronic kidney disease

  This study is testing if the medication dapagliflozin can help slow down kidney problems and lower the risk of heart or kidney-related deaths in adults with advanced chronic kidney disease.

  Recruiting Phase 3 Ain Shams University · Cairo · NCT06982079

• Using advanced MRI techniques to improve breast cancer detection

  This study is testing a new type of MRI that doesn't use contrast dye to see if it can help find and understand breast cancer better in women who are at higher risk or have concerning results.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT06970288

• Ultrasound-guided sacral erector spinae plane block versus saddle block for anesthesia during hemorrhoidectomy

  This will test whether an ultrasound-guided sacral erector spinae plane block works as well as a saddle block for adults having hemorrhoidectomy.

  Recruiting Ain Shams University · Cairo · NCT06969274

• Combining Ketamine and Magnesium for Pain Relief After Nose Surgery

  This study is testing whether combining ketamine and magnesium during nose surgery can help reduce pain and lower the need for opioids afterward.

  Recruiting Ain Shams University · Cairo · NCT06966518

• Examining the link between diabetic neuropathy and muscle mass in type 2 diabetes patients

  This study looks at how diabetic nerve damage affects muscle mass and strength in people over 45 with type 2 diabetes.

  Recruiting at 2 sites Ain Shams University · Cairo, Abbassia and 1 other locations · NCT06958302

• Transplanting insulin-producing stem cells for treating Type 1 Diabetes

  This study is testing whether transplanting insulin-producing stem cells from fat can help people with Type 1 Diabetes better control their blood sugar levels.

  Recruiting Phase 2/3 Ain Shams University · Cairo · NCT06951074

• Comparing two types of nerve blocks for pain relief after breast cancer surgery

  This study is testing which of two nerve block techniques helps women have less pain after breast cancer surgery.

  Recruiting Phase 3 Ain Shams University · Cairo, Waili · NCT06947330

• Probiotics to reduce weight gain from antipsychotic medications

  This study is testing if taking probiotics can help adults with schizophrenia avoid weight gain from their antipsychotic medications.

  Recruiting Phase 3 Ain Shams University · Cairo, Abbassia · NCT06936137

• Assessing Krüppel-Like Factors in Bone Tumors

  This study is testing how certain proteins in bone tumors might affect the outcomes for children and young adults with osteosarcoma and Ewing sarcoma.

  Recruiting at 2 sites Ain Shams University · Cairo and 1 other locations · NCT06935864

• Evaluating mortality predictors in head trauma patients

  This study is trying to see if certain scoring systems can help doctors predict the chances of survival for patients with traumatic brain injuries in the ICU.

  Recruiting Ain Shams University · Cairo · NCT06922396

• Hepatoprotective program for children with acute lymphoblastic leukemia

  This study tests if changes in diet and omega-3 supplements can help protect the livers of children with acute lymphoblastic leukemia during their chemotherapy treatment.

  Recruiting at 2 sites Phase 4 Ain Shams University · Cairo and 1 other locations · NCT06918054

• Using methylprednisolone to prevent kidney injury during heart surgery

  This study is testing if giving a single dose of methylprednisolone during heart surgery can help prevent kidney injury after the operation.

  Recruiting Phase 1 Ain Shams University · Cairo, Abbasia · NCT06917859

• Comparing Interleukin 6 and Procalcitonin for Sepsis Detection in Burn Patients

  This study is testing whether measuring Interleukin-6 can help doctors find sepsis in burn patients better than the usual test with procalcitonin.

  Recruiting Ain Shams University · Cairo · NCT06915974

• Improving lung function in children with cystic fibrosis

  This study is testing a new plan to help improve lung function in children with cystic fibrosis by seeing if personalized treatment can increase their breathing ability over a year.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT06915961

• Evaluating 3D Soft Tissue Simulation for Jaw Surgery

  This study tests if using 3D imaging can help plan jaw surgery better for people with certain facial deformities.

  Recruiting at 2 sites Ain Shams University · Cairo, Abbassia and 1 other locations · NCT06893614

• Comparing two types of nerve blocks for pain relief after breast surgery

  This study is testing which of two types of nerve blocks can better relieve pain for women after breast surgery.

  Recruiting Ain Shams University · Cairo , Abbassya · NCT06873893

• Evaluating spinal anesthesia for infants under 3 months

  This study is testing if spinal anesthesia is a safe and effective option for infants under 3 months who need lower abdominal surgery, to reduce the risks of using general anesthesia.

  Recruiting Ain Shams University · Cairo · NCT06871995

• Comparing two methods for closing the vaginal vault after laparoscopic hysterectomy

  This study is testing two different ways to close the vaginal area after laparoscopic hysterectomy to see which method has fewer complications for women with benign uterine conditions.

  Recruiting Ain Shams University · Cairo · NCT06867614

• Using Perfusion Index to Guide Vasopressor Treatment in Sepsis

  This study is testing if using the perfusion index can help doctors decide when to start a specific medication for ICU patients with sepsis to improve their recovery.

  Recruiting Ain Shams University · Cairo · NCT06860438

• Evaluating a new patient position for kidney stone surgery

  This study is testing if a new way of positioning patients during kidney stone surgery can help them get rid of stones more effectively than the usual position.

  Recruiting Ain Shams University · Cairo, Abbassia, Cairo · NCT06860113

• Protecting the heart during chemotherapy for children with leukemia

  This study tests whether certain heart medications can help protect children with leukemia from heart damage caused by chemotherapy.

  Recruiting at 2 sites Phase 3 Ain Shams University · Cairo and 1 other locations · NCT06853951

• Comparing two nerve blocks for pain control in hip fracture surgeries

  This study is testing which pain relief method, iliopsoas nerve block or femoral nerve block, works better for people having surgery for hip fractures to help them feel more comfortable and move around sooner.

  Recruiting Ain Shams University · Cairo · NCT06852378

• Administering adrenaline in STEMI patients during PCI to prevent no reflow

  This study tests if giving adrenaline during heart procedures can help STEMI patients avoid complications with blood flow without causing heart rhythm problems.

  Recruiting Phase 3 Ain Shams University · Cairo · NCT06847568

• Using Peripheral Perfusion Index to Predict Caudal Block Success in Kids Undergoing Surgery

  This study is testing if a special measurement called the peripheral perfusion index can help predict if a pain relief technique will work for young children having surgery.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT06846983

• Aminophylline to help ureteric access sheath placement during flexible ureteroscopy

  This trial will test whether putting aminophylline into the ureter before flexible ureteroscopy helps place the ureteric access sheath and reduces ureteric injuries for patients with upper ureter or kidney stones smaller than 2 cm.

  Recruiting Ain Shams University · Cairo, Abassia · NCT06830577

• Comparing two pain relief methods for hip surgery

  This study is testing which pain relief method, a fascia iliaca block or a spinal injection of nalbuphine, works better for people recovering from hip surgery.

  Recruiting Ain Shams University · Cairo · NCT06818396

• Comparing two methods of pain management after knee surgery

  This study tests whether a new way of managing pain after knee surgery, using two different blocks, can help patients recover faster and use fewer opioids.

  Recruiting Ain Shams University · Cairo · NCT06802419

• Comparing fixation methods for specific pelvic ring injuries

  This study is testing whether fixing pelvic ring injuries from the front or back first leads to better recovery and fewer problems for people with certain types of pelvic injuries.

  Recruiting Ain Shams University · Cairo · NCT06792305

• Comparing nerve blocks for pain management after shoulder surgery

  This study is testing three different ways to block pain after shoulder surgery to see which one helps patients feel better and recover faster.

  Recruiting Ain Shams University · Cairo · NCT06765278

• Impact of genetic variations on side effects from capecitabine in Egyptian cancer patients

  This study is trying to see how a specific genetic change affects side effects from capecitabine in Egyptian cancer patients being treated for colorectal or breast cancer.

  Recruiting Ain Shams University · Shibīn al Kawm, Menoufia · NCT06765252

• Investigating key epigenetic factors in breast cancer patients

  This study is trying to see if certain genetic markers in newly diagnosed breast cancer patients can help improve how doctors diagnose and treat the disease.

  Recruiting Ain Shams University · Cairo · NCT06759714

• TLR4 gene change and periodontitis in adults with end-stage kidney disease

  This project will test whether a specific TLR4 gene change (rs2149356) is linked to periodontitis in adults aged 30–60 who are on hemodialysis for end-stage kidney disease compared with otherwise healthy adults who also have periodontitis.

  Recruiting Ain Shams University · Al Fayyum, Faiyum Governorate · NCT06755372

• Using ultrasound to assess body composition in critically ill patients

  This study is testing if ultrasound can help doctors see changes in body composition, like muscle loss and fluid shifts, in critically ill patients to improve their recovery.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT06728722

• Manuka honey mouth rinse for people on hemodialysis with periodontitis

  This tests whether a Manuka honey mouth rinse can improve gum disease in adults with end-stage kidney disease who are receiving hemodialysis.

  Recruiting Phase 3 Ain Shams University · Banhā · NCT06726876

• Assessing cognitive and neurophysiological outcomes after open heart surgery

  This study looks at how open heart surgery affects thinking and brain function in patients, using special tests to see if their brain activity before surgery can predict how well they will think afterward.

  Recruiting Ain Shams University · Cairo · NCT06707454

• Testing Rosuvastatin for treating Major Depressive Disorder

  This study is testing if taking Rosuvastatin can help adults aged 20 to 45 with Major Depressive Disorder feel better over three months.

  Recruiting Phase 3 Ain Shams University · Cairo, Al Abbasia · NCT06698666

• Ultrasound assessment of airway difficulties in critically ill preeclamptic patients

  This study tests if using two or five ultrasound views can better predict airway difficulties during cesarean sections for critically ill pregnant women with preeclampsia compared to standard methods.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT06651879

• Comparing two nerve block techniques for pain relief after gallbladder surgery

  This study is testing which of two nerve block methods helps adults feel less pain after gallbladder surgery.

  Recruiting Ain Shams University · Cairo · NCT06588777

• Using Vitamin B Complex for Pain Relief After Cesarean Section

  This study is testing if adding vitamin B complex to standard pain relief methods can help women recover better after a cesarean section while reducing the need for opioids.

  Recruiting Ain Shams University · Cairo, Egypt · NCT06446830

• Restoring non-cavity dental lesions with different materials

  This study is testing different materials and methods to see which works best for treating non-cavity dental lesions in patients.

  Recruiting Ain Shams University · Cairo · NCT06393699

• Individualized PEEP for improving lung function in obese patients after bariatric surgery

  This study tests whether using a personalized breathing support technique can help obese patients breathe better and avoid lung problems after weight loss surgery.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT06168162

• Evaluating lung ultrasound for early detection of ARDS in chest trauma patients

  This study is testing if lung ultrasound can help doctors find early signs of lung problems like ARDS in patients with chest injuries, and how it compares to CT scans.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT06078254

• Effects of Healing Time on Bone Grafting After Tooth Extraction

  This study is testing how waiting different amounts of time after a tooth extraction affects the success of a bone graft to help prepare for dental implants.

  Recruiting Phase 4 Ain Shams University · Cairo · NCT06031298

• Impact of CoQ10 on patients with fatty liver disease

  This study is testing if taking high doses of CoQ10 can help people with fatty liver disease feel better by reducing inflammation and improving their health markers.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT05984745

• Comparing honey and alcohol for skin disinfection

  This study tests whether honey can be a safer and effective skin disinfectant for kids aged 2 to 12 compared to regular alcohol.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT05937412

• Comparing three surgical procedures for hip dislocation in children with cerebral palsy

  This study tests which of three different surgeries works best to fix hip dislocation in children with cerebral palsy who can’t walk.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT05593887

• Comparing two techniques for lifting the maxillary sinus floor during dental implant placement

  This study is testing two different methods for lifting the maxillary sinus during dental implant surgery to see which one works better for patients with missing teeth in the upper jaw.

  Recruiting at 2 sites Ain Shams University · Asyut and 1 other locations · NCT05495490

• Comparing oral pregabalin and fentanyl for pain relief after surgery

  This study is testing whether taking pregabalin before surgery can help manage pain after laparoscopic gynecologic surgery better than using fentanyl during the procedure.

  Recruiting Early Phase 1 Ain Shams University · Cairo · NCT05150795

• Combining low-concentration carbohydrates with nitrates before gynecological surgery

  This study is testing if drinking a mix of low-concentration carbohydrates and nitrates before gynecological surgery can help patients recover better and stay in the hospital for a shorter time.

  Recruiting Phase 4 Ain Shams University · Cairo · NCT04962776

Quick answers

How many clinical trials run by Ain Shams University are recruiting right now?

147, as of November 12, 2026. 6 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in Egypt. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 11, Phase 2: 9, Phase 4: 8, Phase 2/3: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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