Clinical trial Recruiting at 1 site Interventional Ages 21 to 65

Comparing two methods of pain management after knee surgery

Official title: A Comparative Study Between the Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries

Run by Ain Shams University · NCT06802419 · Data updated 2026-11-12

This study tests whether a new way of managing pain after knee surgery, using two different blocks, can help patients recover faster and use fewer opioids.

Quick facts

Study typeInterventional
Ages21 Years to 65 Years
SexAll
Enrollment70 (estimated)
SponsorAin Shams University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedJanuary 30, 2025
Main results expectedOctober 1, 2025
Study endsOctober 1, 2025
Registry record updatedJanuary 31, 2025
Trial IDNCT06802419 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 21 to 65 scheduled for elective arthroscopic knee surgery with successful spinal anesthesia.

Probably not a fit

Patients with contraindications to regional anesthesia, such as coagulopathy or local infection, or those with certain comorbidities like diabetes or psychiatric disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a Continuous Adductor Canal Block alone versus a combination of this block with an additional posterior knee block known as the IPACK block after arthroscopic knee surgeries. The goal is to enhance recovery by providing effective pain relief while preserving motor function, which can facilitate earlier physical therapy and faster recovery. The study focuses on patients undergoing elective surgeries for ACL and PCL repairs, aiming to reduce opioid use and improve postoperative outcomes.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and quicker recovery for patients undergoing knee surgery.

How similar studies have gone: Other studies have shown promising results with similar nerve block techniques, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age from 21 to 65 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) Physical Status Class I to II.
* Patients with successful spinal anesthesia.
* Patients scheduled for elective arthroscopic knee surgery for anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) repair.

Exclusion Criteria:

* Declining to give written informed consent.
* History of allergy to the medications used in the study.
* Contraindications to regional anesthesia (including coagulopathy and local infection).
* Polytrauma patients having lower limb fractures.
* Patients with pre-existing myopathy or neuropathy on the operating limb.
* Patients with diabetes mellitus.
* Psychiatric disorder.
* Morbid obesity \[body mass index (BMI) \> 45kg/m2\].
* Complicated Surgery.

Where it's running

  • Ain Shams University
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.