Combining Ketamine and Magnesium for Pain Relief After Nose Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of using a combination of ketamine and magnesium sulfate infusions during surgery to improve pain management after open rhinoplasty. By targeting NMDA receptors in the nervous system, the study aims to reduce postoperative pain and decrease the need for opioids. The approach is based on the premise that the two substances can work synergistically to enhance analgesia. Patients undergoing this procedure will be monitored for pain levels and opioid consumption post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 65 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I - II.
* Scheduled for rhinoplasty under general anesthesia.

Exclusion Criteria:

* Receiving analgesic or any medications since 48 hours before the surgery.
* Drug addiction.
* Cardiovascular disease.
* Respiratory disease, renal, liver, metabolic and neurological disease.
* Pregnancy or breast feeding.
* Asthma.

Where it's running

• Ain Shams University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Sarah A Afifi, MD
• Email: Sarah606060@gmail.com
• Phone: 0501035864

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.