Mini‑PCNL versus flexible ureteroscopy with a suction sheath for 2–3 cm kidney stones

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized interventional trial assigns adults with 2–3 cm renal stones to either mini‑percutaneous nephrolithotomy (mini‑PCNL) or flexible ureteroscopy (FURS) using a navigable suction sheath. Mini‑PCNL creates a small tract through the back into the kidney to directly visualize and remove stones with a miniature nephroscope. FURS is performed through the urinary tract using a thin flexible scope that incorporates suction to help capture and remove fragments and limit retropulsion. The primary outcome is stone‑free rate on post‑operative imaging, with secondary outcomes including operative time, length of hospital stay, and complication rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients aging 18 years old or more.
* Patients with renal stones between 2-3 cm in size confirmed by CT scan.

Exclusion Criteria:

* Patients with previous ureteric injury.
* Patients with uncontrolled diabetes mellitus or hypertension.
* Patients with uncontrolled hepatic dysfunction.
* Patients with uremia or renal failure.
* Pregnant patients.
* patients with active urinary tract infection.
* Patients with bleeding tendency or uncontrolled coagulopathy.
* Patients with congenital anomalies as horse-shoe kidney and pelvi-ureteric junction obstruction.

Where it's running

• Ain shams university hospitals
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed M Hasab Allah, resident
• Email: Mohamed-Hasaballah@med.asu.edu.eg
• Phone: +201012663766

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.