Using blood cell ratios and procalcitonin to predict outcomes for adults with sepsis in the ICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational ICU study that will collect routine laboratory values (neutrophil-to-lymphocyte-and-platelet ratio, procalcitonin, and total leukocyte count) from adult patients diagnosed with sepsis. Researchers will compare these biomarkers to patients' clinical outcomes such as mortality, organ failure, and length of ICU stay to see which markers best correlate with prognosis. The study excludes patients with pregnancy, malignancy, immunosuppression, hematologic disorders, major trauma or burns, advanced liver cirrhosis, or those on hemodialysis. No investigational treatments are given; data are drawn from standard care blood tests and clinical records.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 70 years old.
* Both sexes.
* Septic patients (under the third international consensus definitions of sepsis and septic shock).

Exclusion Criteria:

* Pregnancy
* Malignancy
* On immunosuppressive therapy
* Hematological Disorders
* Major Trauma
* Major Burns
* Child-Pugh Class C Liver Cirrhosis
* On Hemodialysis

Where it's running

• Ain Shams University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Michael G Farag, Master
• Email: MICHAELFARAG@med.asu.edu.eg
• Phone: 00201278142328

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Genomic changes of Klebsiella pneumoniae and Enterobacter cloacae in ICU patients over time

  This study tests how the gut bacteria Klebsiella pneumoniae and Enterobacter cloacae evolve over time in adults in ICUs.

  Recruiting University Hospital, Caen · Caen · NCT07744321

• Two eye care methods to prevent eye problems in ventilated ICU patients

  This tests whether using an eye care kit, a written eye-care protocol, or both will reduce eye complications compared with standard care in adults on mechanical ventilation in the ICU.

  Recruiting Istanbul Saglik Bilimleri University · Istanbul, Istanbul · NCT07070843

• Autologous Cold-Stored Platelets for Complex Cardiac Surgery

  This study tests whether using a patient’s own cold-stored platelets, donated 7–10 days before surgery, improves outcomes for adults undergoing complex cardiac procedures compared with standard allogeneic platelets.

  Recruiting Phase 2/3 University Health Network, Toronto · Toronto, Ontario · NCT07064954

• Virtual reality to improve comfort for adults in the surgical ICU

  This trial will try immersive virtual reality (HypnoVR) sessions to reduce discomfort for adults who stay at least 48 hours in the surgical intensive care unit after major cardiothoracic or abdominal surgery.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06830369

• Using a device to recover platelets during cardiac surgery

  This study tests if a special device that collects and returns your own blood during heart surgery can help keep your platelet levels up and reduce the need for blood transfusions.

  Recruiting University Hospital, Strasbourg, France · Strasbourg, Bas-Rhin · NCT06629311

• Calibration of esophageal balloon catheter for patients on mechanical ventilation

  This study is testing how to better calibrate a special balloon used in the esophagus to measure pressure in patients on mechanical ventilation, to see if it helps improve their care.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT06584604

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.