Flexible Ureteroscopy With Navigable Suction vs Mini-PCNL in Kids with Kidney Stones
Official title: A Comparative Study on the Efficacy and Safety of Flexible Ureteroscopy With Flexible Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheath for the Management of Renal Stones 1- 2.5 cm in Pediatric Age Group
Run by Ain Shams University · NCT07763743 · Data updated 2026-11-12
This study tests whether flexible ureteroscopy with suction helps treat kidney stones in children compared with mini-percutaneous nephrolithotomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 1 Year to 14 Years |
| Sex | All |
| Enrollment | 72 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Cairo, Abbasia) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | June 1, 2027 |
| Study ends | June 10, 2027 |
| Registry record updated | August 13, 2026 |
| Trial ID | NCT07763743 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pediatric patients with a renal stone burden of 1 to 2.5 cm and no contraindicating infections, coagulation disorders, or anatomical factors precluding either procedure.
✕Probably not a fit
Patients with stones outside the 1–2.5 cm range, active untreated infection, uncorrected coagulopathy, or anatomy that prevents either procedure may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two surgical approaches for pediatric renal stones up to 2.5 cm: flexible ureteroscopy with a navigable suction ureteral access sheath versus mini-percutaneous nephrolithotomy with a vacuum-assisted access sheath. It will look at safety and effectiveness, including stone clearance, operative factors, and complication rates. Eligible participants are children with imaging-confirmed stones and no contraindicating conditions. The investigation aims to determine if suction-assisted techniques improve outcomes in pediatric stone management across these two commonly used procedures.
Why it matters
Potential benefit: If successful, suction-assisted flexible ureteroscopy could offer safer and more effective stone clearance with fewer complications in children.
How similar studies have gone: Preliminary data in adults and select pediatric series suggest suction-assisted approaches may improve visibility, reduce operative time, and increase stone clearance, but pediatric evidence remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Renal stone burden 1- 2.5 cm confirmed by imaging (CT or ultrasound). Exclusion Criteria: * Patients who refuse to participate in the study. * Untreated Urinary tract infection (UTI) proved by urine culture and sensitivity. * Uncorrected coagulopathy. * Anatomical anomalies or ureteral stricture precluding either surgical approach. * Previous surgical intervention on the same kidney.
Where it's running
-
Ain Shams University Hospitals
Cairo, Abbasia, Egypt Recruiting
Study contacts
- Study coordinator: Mohamed Ramadan Mohamed Ramadan, MSc
- Email: DR.MohamedRamadan@med.asu.edu.eg
- Phone: +201005229645
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.