HVGIC versus bulk‑fill composite for moderate Class II posterior cavities
Official title: Clinical Performance of Highly Viscous Glass Ionomer Versus Bulk Fill Resin Composite Restorative Materials in Moderate Class II Cavities of Permanent Posterior Teeth " A 12-Month Randomized Clinical Study"
Run by Ain Shams University · NCT07067164 · Data updated 2026-11-12
This study will test whether highly viscous glass ionomer or a bulk‑fill resin composite works better for moderate Class II cavities in adults who have at least two such lesions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 31 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | July 2025 |
| Main results expected | July 2026 |
| Study ends | September 2026 |
| Registry record updated | July 16, 2025 |
| Trial ID | NCT07067164 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–45 who are systemically healthy with at least two moderate Class II carious lesions in permanent posterior teeth, vital symptom‑free teeth, and good periodontal health are ideal candidates.
✕Probably not a fit
Patients who are medically compromised, pregnant or breastfeeding, have poor oral hygiene, bruxism, extensive lesions needing cusp coverage, or fewer than two eligible lesions are unlikely to qualify or derive benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In a prospective, randomized split‑mouth design, 31 adult patients with at least two moderate Class II lesions receive one HVGIC restoration on one side and a bulk‑fill resin composite on the other. Restorations are evaluated at baseline (1 week), 6 months, and 12 months using the modified USPHS criteria with marginal adaptation as the primary outcome. Secondary outcomes include anatomic form, contact point, retention, marginal discoloration, surface texture, color match, secondary caries, and postoperative sensitivity. The trial is conducted at the Faculty of Dentistry, Ain Shams University in Cairo.
Why it matters
Potential benefit: If successful, the results could help clinicians choose a simpler or more durable restorative material and reduce the need for repairs or replacements.
How similar studies have gone: Previous short‑term clinical studies have shown comparable 6–12 month performance for modern bulk‑fill composites and improved HVGIC formulations, but long‑term comparative data remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients aged 18 to 45 years 2. Systemically healthy individuals 3. Patients with at least two Class II carious lesions (one on each side) in permanent posterior teeth 4. Vital, symptomless teeth 5. Teeth in occlusion and in contact with adjacent natural teeth 6. Healthy periodontal tissues 7. Carious lesions of moderate depth (outer or middle third of dentin radiographically) 8. Patients likely to return for recall visits Exclusion Criteria: 1. Medically compromised patients 2. Pregnant or breastfeeding women 3. Poor oral hygiene 4. Patients undergoing orthodontic treatment 5. Patients with parafunctional habits (e.g., bruxism) 6. Extensive lesions requiring cusp coverage 7. Absence of adjacent or opposing teeth
Where it's running
-
Faculty of Dentistry, Ain Shams University
Cairo, Cairo Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Mohamed A Kamel, PhD — Associate Professor of Operative Dentistry Faculty of Dentistry Ain Shams University
- Study coordinator: Noha M Anany, MSc
- Email: nohaanany252@gmail.com
- Phone: 002/01000511714
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.