Comparing two nerve block techniques for pain relief after gallbladder surgery
Official title: Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy
Run by Ain Shams University · NCT06588777 · Data updated 2026-11-12
This study is testing which of two nerve block methods helps adults feel less pain after gallbladder surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 71 Years |
| Sex | All |
| Enrollment | 52 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | September 1, 2024 |
| Main results expected | December 30, 2025 |
| Study ends | December 30, 2025 |
| Registry record updated | September 30, 2025 |
| Trial ID | NCT06588777 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 21 to 70 years undergoing laparoscopic cholecystectomy with ASA physical status classes I or II.
✕Probably not a fit
Patients with ASA physical status classes III or above, coagulopathy, or local anesthetic allergies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of two different nerve block techniques, the modified thoracoabdominal nerve block through a perichondrial approach (M-TAPA) and the quadratus lumborum block, for providing postoperative pain relief in patients undergoing laparoscopic cholecystectomy. The trial will involve adult patients aged 21 to 70 years who are classified as ASA physical status I or II. The goal is to determine which technique offers better analgesia following surgery under general anesthesia.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic cholecystectomy.
How similar studies have gone: Other studies have shown promising results with similar nerve block techniques, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients aging ≥ 21 years to ≤ 70 of both sexes. * Patients undergoing Laparoscopic cholecystectomy surgeries. * ASA physical status classes I - II. Exclusion Criteria: * Patient's refusal of procedure or participation in the study. * ASA classes III or above. * Coagulopathy and bleeding disorders. * Evidence of Local skin infections at site of injection. * Body mass index \>40kg/m2 * A history of relevant local anesthetic allergy.
Where it's running
-
Ainshams university hospitals
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Ahmed Hassan, Master
- Email: ahmedhassan199466@gmail.com
- Phone: 01158195158
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Erector Spinae Plane Block vs Modified Thoracoabdominal Nerve Block After Laparoscopic Cholecystectomy
Two regional anesthesia techniques are being tested to see which provides better pain control after gallbladder removal surgery.
-
Subcostal TAP Block and EEG Changes During Laparoscopic Gallbladder Surgery
This observational study tests whether adding a subcostal TAP block to standard IV opioid therapy affects intraoperative brain activity measures and pain needs in adults undergoing laparoscopic cholecystectomy.
-
Dexmedetomidine vs magnesium as intraperitoneal add-ons to bupivacaine for laparoscopic gallbladder removal
This study tests whether adding dexmedetomidine or magnesium sulfate to bupivacaine injected inside the abdomen provides better pain relief after laparoscopic cholecystectomy for adults without serious health issues.
-
How different ventilator settings affect lung energy during gallbladder surgery
This study tests whether two ventilator modes (VCV and PRVC) deliver different amounts of energy to the lungs in adults undergoing laparoscopic gallbladder removal.
-
Erector Spinae Plane Block with Low-Flow Anaesthesia in Laparoscopic Cholecystectomy
This trial tests whether a nerve block done before surgery plus very low-flow anesthesia reduces pain and opioid use after gallbladder removal.
-
Pre-incisional ropivacaine plus Diprospan for pain after laparoscopic surgery
This study tests whether injecting ropivacaine with Diprospan before surgery reduces pain after laparoscopic gallbladder, appendix, or hernia operations compared with ropivacaine alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.