Clinical trial Recruiting at 1 site Interventional Ages 21 to 71

Comparing two nerve block techniques for pain relief after gallbladder surgery

Official title: Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Run by Ain Shams University · NCT06588777 · Data updated 2026-11-12

This study is testing which of two nerve block methods helps adults feel less pain after gallbladder surgery.

Quick facts

Study typeInterventional
Ages21 Years to 71 Years
SexAll
Enrollment52 (estimated)
SponsorAin Shams University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedSeptember 1, 2024
Main results expectedDecember 30, 2025
Study endsDecember 30, 2025
Registry record updatedSeptember 30, 2025
Trial IDNCT06588777 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 21 to 70 years undergoing laparoscopic cholecystectomy with ASA physical status classes I or II.

Probably not a fit

Patients with ASA physical status classes III or above, coagulopathy, or local anesthetic allergies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of two different nerve block techniques, the modified thoracoabdominal nerve block through a perichondrial approach (M-TAPA) and the quadratus lumborum block, for providing postoperative pain relief in patients undergoing laparoscopic cholecystectomy. The trial will involve adult patients aged 21 to 70 years who are classified as ASA physical status I or II. The goal is to determine which technique offers better analgesia following surgery under general anesthesia.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic cholecystectomy.

How similar studies have gone: Other studies have shown promising results with similar nerve block techniques, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients aging ≥ 21 years to ≤ 70 of both sexes.
* Patients undergoing Laparoscopic cholecystectomy surgeries.
* ASA physical status classes I - II.

Exclusion Criteria:

* Patient's refusal of procedure or participation in the study.
* ASA classes III or above.
* Coagulopathy and bleeding disorders.
* Evidence of Local skin infections at site of injection.
* Body mass index \>40kg/m2
* A history of relevant local anesthetic allergy.

Where it's running

  • Ainshams university hospitals
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.