Comparing two nerve block techniques for pain relief after gallbladder surgery

Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Not applicable Interventional Ain Shams University · NCT06588777

This study is testing which of two nerve block methods helps adults feel less pain after gallbladder surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment52 (estimated)
Ages21 Years to 71 Years
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06588777 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of two different nerve block techniques, the modified thoracoabdominal nerve block through a perichondrial approach (M-TAPA) and the quadratus lumborum block, for providing postoperative pain relief in patients undergoing laparoscopic cholecystectomy. The trial will involve adult patients aged 21 to 70 years who are classified as ASA physical status I or II. The goal is to determine which technique offers better analgesia following surgery under general anesthesia.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 21 to 70 years undergoing laparoscopic cholecystectomy with ASA physical status classes I or II.

Not a fit: Patients with ASA physical status classes III or above, coagulopathy, or local anesthetic allergies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic cholecystectomy.

How similar studies have performed: Other studies have shown promising results with similar nerve block techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients aging ≥ 21 years to ≤ 70 of both sexes.
* Patients undergoing Laparoscopic cholecystectomy surgeries.
* ASA physical status classes I - II.

Exclusion Criteria:

* Patient's refusal of procedure or participation in the study.
* ASA classes III or above.
* Coagulopathy and bleeding disorders.
* Evidence of Local skin infections at site of injection.
* Body mass index \>40kg/m2
* A history of relevant local anesthetic allergy.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Laparoscopic CholecystectomyModified Thoracoabdominal Nerve BlockQuadratus Lumborum BlockLaparoscopic cholecystectomymodified thoracoabdominal nerve blockquadratus lumborum block
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.