Dynamic navigation versus pre-made guides for placing upper-jaw dental implants

Accuracy Assessment of Dynamic Vs. Static Navigation Implant Placement Protocols (Randomized Controlled Trial)

PHASE4 · Ain Shams University · NCT07291336

This will test whether using a real-time dynamic navigation screen or a pre-made surgical guide gives more accurate implant placement for healthy adults missing an upper tooth.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment20 (estimated)
Ages22 Years to 60 Years
SexAll
SponsorAin Shams University (other)
Locations1 site (Cairo)
Trial IDNCT07291336 on ClinicalTrials.gov

What this trial studies

Participants who are at least 22 years old and meet bone and tooth-count requirements will have implant placement planned from x-rays and impressions. They will be assigned to either a static workflow using a fabricated surgical guide or a dynamic navigation workflow where the surgeon follows real-time screen guidance during drilling and implant insertion. Accuracy of the final implant position will be measured against the preoperative plan to compare the two approaches. All procedures and follow-up visits take place at the dental faculty site in Cairo and standard clinical safety criteria are applied.

Who should consider this trial

Good fit: Ideal candidates are healthy adults aged 22 or older with at least one missing tooth in the upper jaw between the right and left second premolars, at least six remaining teeth in that jaw, and at least 5 mm of available bone.

Not a fit: Patients who need bone augmentation, have poor oral hygiene, heavy smoking, uncontrolled systemic disease, pregnancy, or prior head/neck radiotherapy are unlikely to benefit or be eligible for this protocol.

Why it matters

Potential benefit: If successful, the comparison could identify a method that improves implant placement accuracy and reduces positioning errors and complications.

How similar studies have performed: Prior clinical work has shown mixed but generally favorable results for dynamic navigation, with some studies reporting similar or improved placement accuracy compared with static guides.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy patients at least 22 years old.

  * At least one missing tooth to be restored using an implant in the upper jaw from the maxillary right 2nd premolar to the maxillary left 2nd premolar.
  * At least six residual teeth in the affected jaw (5).
  * Minimum of 5 mm available bone.

Exclusion Criteria:

* Medical condition or medication that would impair bone healing.

  * Poor oral hygiene
  * Inadequate bone width or height that may need bone augmentation. 5
  * Alcohol users.
  * Smoking more than 10 cigarettes per day.
  * History of head and neck radiotherapy.
  * Pregnant females.
  * Uncontrolled hypertensive or diabetic patient.
  * Vulnerable group; prisoners, pregnant women, orphans…etc

Where this trial is running

Cairo

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Healthy Adults, Dental Implant, Accuracy, dynamic navigation, static navigation, guide, delayed implant

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.