Dexmedetomidine added to bupivacaine caudal block for children having open appendectomy.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children (ASA I–II) undergoing open appendectomy under general anesthesia at Ain Shams University will receive a caudal block with either bupivacaine alone or bupivacaine plus dexmedetomidine. Investigators will record pain scores, duration of postoperative analgesia, time to first analgesic request, opioid consumption, incidence of emergence delirium, and any adverse events. Recovery quality measures and safety monitoring will be compared between the two groups. Standard anesthetic care will be maintained for all participants.

Why it matters

Who can join: the full rules

inclusion criteria:

* ASA (American Society of Anesthesiologists) physical status I or II.
* Legal guardian provides written informed consent. Exclusion Criteria
* Refusal of participation by the legal guardian.
* Known allergy or hypersensitivity to local anesthetics or dexmedetomidine.
* Coagulation disorder or receiving anticoagulant therapy.
* Active infection at or near the injection site.
* Significant anatomical abnormalities of the lumbosacral spine.
* Pre-existing neurological disorders, psychiatric disorders, or a history of convulsions.
* Anticipated surgery time of more than 2.5 hours.
* Patients with severe asthma or active wheezing.

Where it's running

• Ain Shams university hospitals
  Cairo, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.