Individualized PEEP for improving lung function in obese patients after bariatric surgery
Effect of Individualized High Positive End-expiratory Pressure on Postoperative Pulmonary Rate in Laparoscopic Bariatric Surgeries
This study tests whether using a personalized breathing support technique can help obese patients breathe better and avoid lung problems after weight loss surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 16 Years and up |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Trial ID | NCT06168162 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of individualized high positive end-expiratory pressure (PEEP) on postoperative pulmonary complications in obese patients undergoing laparoscopic bariatric surgery. It aims to compare the outcomes of patients receiving optimized PEEP tailored to their lung mechanics against those receiving standard PEEP. The study focuses on enhancing oxygenation and lung function during and after surgery to reduce the risk of complications. Participants will be monitored for postoperative pulmonary complications to assess the effectiveness of the intervention.
Who should consider this trial
Good fit: Ideal candidates are obese patients aged 18 to 60 with a BMI over 40 scheduled for elective laparoscopic bariatric surgery.
Not a fit: Patients with previous lung surgery, severe lung disease, or those requiring postoperative mechanical ventilation may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of postoperative pulmonary complications in obese patients undergoing bariatric surgery.
How similar studies have performed: Previous studies have shown that protective lung ventilation strategies can improve outcomes in similar patient populations, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients were eligible for participation if the met the following criteria * Age between 18 and 60 years old. * Body mass index \> 40 * Laparoscopic bariatric elective surgery under general anesthesia. * ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC. Exclusion Criteria: * Previous lung surgery * ASA status III or IV. * Moderate to severe obstructive or restrictive lung disease . * Persistant intraoperative hemodynamic instability . * Need for postoperative mechanical ventilation
Where this trial is running
Cairo, Cairo Governorate
- Ain shams university — Cairo, Cairo Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: wessam selima, MD
- Email: w.z.selima@med.asu.edu.eg
- Phone: +201001958858
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.