Using advanced MRI techniques to improve breast cancer detection
Effectiveness of Introducing Ultra-High B-Value Diffusion-Weighted Imaging as a Modified Abbreviated Protocol for Breast Cancer Detection
This study is testing a new type of MRI that doesn't use contrast dye to see if it can help find and understand breast cancer better in women who are at higher risk or have concerning results.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 85 (estimated) |
| Ages | 30 Years to 50 Years |
| Sex | Female |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Abbasia) |
| Trial ID | NCT06970288 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a non-contrast abbreviated MRI protocol that incorporates ultra-high B-value Diffusion Weighted Imaging for detecting and characterizing suspicious breast lesions. The goal is to enhance breast cancer detection while avoiding the use of contrast agents, which can pose risks for some patients. Women with specific risk factors or suspicious findings will be included in the study to assess the protocol's performance in a real-world setting.
Who should consider this trial
Good fit: Ideal candidates include women with suspicious breast masses, high-risk women with a positive family history, and those with dense breasts requiring MRI imaging.
Not a fit: Patients with contraindications to MRI or those who have previously undergone treatment or intervention for breast issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to safer and more effective breast cancer detection methods for patients.
How similar studies have performed: While this approach is innovative, similar studies using advanced MRI techniques have shown promise in improving cancer detection rates.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Women with suspicious breast mass (BIRADS 4a) * High risk women (Positive family history) * Women with suspicious axillary lymph nodes by Ultrasound * Women with dense breasts coming for MRI imaging. Exclusion Criteria: * • Contraindications to MRI * Pacemaker, cochlear implant, claustrophobia, ocular implants * Contraindications to contrast administration: * Elevated kidney functions * Women who haven't undergone reliable Mammogram \& Ultrasound * Women with prior treatment or intervention (e.g. biopsy) * Patients' refusal.
Where this trial is running
Cairo, Abbasia
- Ain Shams University — Cairo, Abbasia, Egypt (Recruiting)
Study contacts
- Study coordinator: Ahmed Mohamed Aly
- Email: ahmedaly@med.asu.edu.eg
- Phone: +201273726233
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.