How to size a child’s breathing tube using ultrasound versus age-based formulas
Official title: Comparison of Age-Based Formula and Ultrasound-Guided Subglottic Diameter Measurement for Endotracheal Tube Sizing in Single Ventricle Patients
Run by Ain Shams University · NCT07586592 · Data updated 2026-11-12
This study tests whether ultrasound measurements of the throat can help pick the right endotracheal tube size for children with single-ventricle hearts, potentially reducing trouble after intubation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 3 Months to 8 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Abbasseya) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT07586592 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 3 months to 8 years with single ventricle physiology undergoing Glenn/Fontan surgery or related catheterization, without tracheostomy or active airway infection.
✕Probably not a fit
Children outside the specified age range or without single ventricle physiology, or those with airway anomalies or recent upper airway infection may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this interventional study, pediatric patients aged 3 months to 8 years with single ventricle physiology undergoing Glenn/Fontan-related procedures or cardiac catheterization will be randomized to sizing by ultrasound-guided subglottic diameter or by age-based formulas. The trial compares the accuracy of ultrasound measurement to traditional weight/age-based sizing to determine the optimal endotracheal tube (ETT) size and reduce post-extubation complications. Standard anesthesia and monitoring procedures will be used, with informed consent obtained from guardians. Data collection will include demographic information, cardiac status, and intraoperative airway measurements. The goal is to see if ultrasound can improve tube fit and safety in this high-risk pediatric population.
Why it matters
Potential benefit: If successful, ultrasound-guided sizing could improve airway safety and reduce post-extubation complications for children with single-ventricle physiology.
How similar studies have gone: Previous work suggests ultrasound-based airway assessments can improve tube sizing in some pediatric populations, but this specific approach in single-ventricle patients is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients (3 months to 8 years) * Patients with single ventricle physiology * Scheduled for Glenn or Fontan surgery or cardiac catheterization * Patients with Glenn or Fontan shunt scheduled for surgery Exclusion Criteria: * Refusal of legal guardians * Emergency surgery * Patients with tracheostomy tubes * Recent or active upper respiratory tract infection * Airway anomalies (e.g. Pierre Robin, Treacher Collins) * ICU stay due to complications other than that of airway
Where it's running
-
Ain Shams University
Cairo, Abbasseya, Egypt Recruiting
Study contacts
- Study coordinator: Nouran Nemr, M.B.B.Ch, M.Sc.
- Email: Nourannemr@med.asu.edu.eg
- Phone: 01008558583
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.