Clinical trial Recruiting at 1 site Observational Ages 18 and up

Long-term follow up after transvaginal cystocele repair with four-armed collagen-coated mesh

Official title: Long Term Follow Up Of Transvaginal Cystocele Repair Using Four Armed Collagen Coated Polyester Mesh; Retrospective Cohort Study With Prospective Long-term Follow-up

Run by Ain Shams University · NCT07730749 · Data updated 2026-11-12

This study tests whether a four-armed collagen-coated polyester mesh used in transvaginal cystocele repair remains safe and effective more than five years after surgery in women who had the procedure.

More Long Term Follow-Up trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment20 (estimated)
SponsorAin Shams University
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Cairo, Cairo Governorate)
StatusRecruiting
StartedJune 29, 2026
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedJuly 28, 2026
Trial IDNCT07730749 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women who underwent transvaginal cystocele repair using four-armed collagen-coated polyester mesh at Ain Shams University and have at least five years of postoperative follow-up with complete medical records.

Probably not a fit

Patients with incomplete follow-up or records, or those who had pelvic radiation/laser/chemotherapy or uncontrolled diabetes postoperatively, may not benefit from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study looks at long-term safety and effectiveness of transvaginal cystocele repair using a four-armed collagen-coated polyester mesh. It analyzes patients with at least five years of follow-up data to identify durability of the repair and potential late complications. The study focuses on outcomes such as recurrence, mesh-related adverse events, and overall pelvic floor function. Data are gathered from Ain Shams University in Cairo, with inclusion criteria requiring complete follow-up and medical records. Exclusion criteria remove patients with missing data, pelvic radiation/laser/chemotherapy, or uncontrolled diabetes postoperatively.

Why it matters

Potential benefit: If successful, the approach could inform long-term management of anterior vaginal wall prolapse and guide decision-making about mesh-based repairs.

How similar studies have gone: Previous analyses of mesh-based cystocele repairs have shown mixed long-term durability and notable mesh-related complications, making long-term data valuable and somewhat novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

• Data of patients who underwent transvaginal cystocele repair using four-armed collagen coated polyester mesh

Exclusion Criteria:

* Patients with insufficient postoperative follow-up data.
* Patients with incomplete or missing medical records.
* Patients undergone radiation, laser therapy, or chemotherapy in the pelvic area postoperatively.
* Patients newly discovered uncontrolled diabetes mellitus.

Where it's running

  • Ain Shams University
    Cairo, Cairo Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.