Long-term follow up after transvaginal cystocele repair with four-armed collagen-coated mesh
Official title: Long Term Follow Up Of Transvaginal Cystocele Repair Using Four Armed Collagen Coated Polyester Mesh; Retrospective Cohort Study With Prospective Long-term Follow-up
Run by Ain Shams University · NCT07730749 · Data updated 2026-11-12
This study tests whether a four-armed collagen-coated polyester mesh used in transvaginal cystocele repair remains safe and effective more than five years after surgery in women who had the procedure.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | June 29, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | July 28, 2026 |
| Trial ID | NCT07730749 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women who underwent transvaginal cystocele repair using four-armed collagen-coated polyester mesh at Ain Shams University and have at least five years of postoperative follow-up with complete medical records.
✕Probably not a fit
Patients with incomplete follow-up or records, or those who had pelvic radiation/laser/chemotherapy or uncontrolled diabetes postoperatively, may not benefit from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study looks at long-term safety and effectiveness of transvaginal cystocele repair using a four-armed collagen-coated polyester mesh. It analyzes patients with at least five years of follow-up data to identify durability of the repair and potential late complications. The study focuses on outcomes such as recurrence, mesh-related adverse events, and overall pelvic floor function. Data are gathered from Ain Shams University in Cairo, with inclusion criteria requiring complete follow-up and medical records. Exclusion criteria remove patients with missing data, pelvic radiation/laser/chemotherapy, or uncontrolled diabetes postoperatively.
Why it matters
Potential benefit: If successful, the approach could inform long-term management of anterior vaginal wall prolapse and guide decision-making about mesh-based repairs.
How similar studies have gone: Previous analyses of mesh-based cystocele repairs have shown mixed long-term durability and notable mesh-related complications, making long-term data valuable and somewhat novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: • Data of patients who underwent transvaginal cystocele repair using four-armed collagen coated polyester mesh Exclusion Criteria: * Patients with insufficient postoperative follow-up data. * Patients with incomplete or missing medical records. * Patients undergone radiation, laser therapy, or chemotherapy in the pelvic area postoperatively. * Patients newly discovered uncontrolled diabetes mellitus.
Where it's running
-
Ain Shams University
Cairo, Cairo Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Ibrahem M Abdelghany, MBBCH
- Email: IbrahemAbdelghany@med.asu.edu.eg
- Phone: 00201063256605
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.