Clinical trial Recruiting at 1 site Interventional Women only

Using Vitamin B Complex for Pain Relief After Cesarean Section

Official title: The Analgesic Efficacy of Vitamin B Complex with Paracetamol and Non-steroidal Antiinflammatory Medication in Critically Ill Obstetrics After Caesarian Section; a Prospective Randomized , Placebo-controlled and Double-blinded Study

Run by Ain Shams University · NCT06446830 · Data updated 2026-11-12

This study is testing if adding vitamin B complex to standard pain relief methods can help women recover better after a cesarean section while reducing the need for opioids.

Quick facts

Study typeInterventional
SexWomen only
Enrollment100 (estimated)
SponsorAin Shams University
Academic / other
Locations1 site (Cairo, Egypt)
StatusRecruiting
StartedMay 25, 2024
Main results expectedNovember 1, 2025
Study endsDecember 1, 2025
Registry record updatedFebruary 17, 2025
Trial IDNCT06446830 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are critically ill obstetric patients scheduled for cesarean delivery under neuraxial anesthesia.

Probably not a fit

Patients with known allergies to the components of the vitamin B complex or those with severe organ dysfunction may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of vitamin B complex in enhancing pain relief for critically ill obstetric patients following cesarean sections, alongside a standard opioid-sparing multimodal analgesia regimen. The goal is to improve postoperative recovery while minimizing the side effects commonly associated with opioid use. By focusing on a multimodal approach, the study aims to promote better mobility, oral intake, and overall recovery for both the mother and infant. The research is particularly relevant given the unique challenges of pain management in obstetric care.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and recovery outcomes for mothers after cesarean sections.

How similar studies have gone: While the use of multimodal analgesia is well-established, the specific application of vitamin B complex in this context is relatively novel and has not been extensively tested in similar studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Critically ill -obstetric patients who will be delivered by cesarean section under neuraxial anesthesia.

Exclusion Criteria:

1. Patient's Refusal to participate
2. Known allergy to one or more of the given components.
3. Disturbed conscious level.
4. Prolonged or complicated surgery; defined by operative time of more than 90 min.
5. Severe liver dysfunction or failure
6. Severe renal dysfunction or failure.
7. Severe thrombocytopenia; platelets less than 50

Where it's running

  • Ain shams university
    Cairo, Egypt, Egypt
    Recruiting

Study contacts

  • Principal investigator: wessam selima, MD — assistant professor (lecturer)- Ain shams university
  • Study coordinator: wessam selima, MD
  • Email: w.z.selima@med.asu.edu.eg
  • Phone: 01001958858

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.