Using Vitamin B Complex for Pain Relief After Cesarean Section
Official title: The Analgesic Efficacy of Vitamin B Complex with Paracetamol and Non-steroidal Antiinflammatory Medication in Critically Ill Obstetrics After Caesarian Section; a Prospective Randomized , Placebo-controlled and Double-blinded Study
Run by Ain Shams University · NCT06446830 · Data updated 2026-11-12
This study is testing if adding vitamin B complex to standard pain relief methods can help women recover better after a cesarean section while reducing the need for opioids.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Egypt) |
| Status | Recruiting |
| Started | May 25, 2024 |
| Main results expected | November 1, 2025 |
| Study ends | December 1, 2025 |
| Registry record updated | February 17, 2025 |
| Trial ID | NCT06446830 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are critically ill obstetric patients scheduled for cesarean delivery under neuraxial anesthesia.
✕Probably not a fit
Patients with known allergies to the components of the vitamin B complex or those with severe organ dysfunction may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of vitamin B complex in enhancing pain relief for critically ill obstetric patients following cesarean sections, alongside a standard opioid-sparing multimodal analgesia regimen. The goal is to improve postoperative recovery while minimizing the side effects commonly associated with opioid use. By focusing on a multimodal approach, the study aims to promote better mobility, oral intake, and overall recovery for both the mother and infant. The research is particularly relevant given the unique challenges of pain management in obstetric care.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and recovery outcomes for mothers after cesarean sections.
How similar studies have gone: While the use of multimodal analgesia is well-established, the specific application of vitamin B complex in this context is relatively novel and has not been extensively tested in similar studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Critically ill -obstetric patients who will be delivered by cesarean section under neuraxial anesthesia. Exclusion Criteria: 1. Patient's Refusal to participate 2. Known allergy to one or more of the given components. 3. Disturbed conscious level. 4. Prolonged or complicated surgery; defined by operative time of more than 90 min. 5. Severe liver dysfunction or failure 6. Severe renal dysfunction or failure. 7. Severe thrombocytopenia; platelets less than 50
Where it's running
-
Ain shams university
Cairo, Egypt, Egypt Recruiting
Study contacts
- Principal investigator: wessam selima, MD — assistant professor (lecturer)- Ain shams university
- Study coordinator: wessam selima, MD
- Email: w.z.selima@med.asu.edu.eg
- Phone: 01001958858
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Intrathecal versus epidural morphine for pain after cesarean delivery
This test will compare a single intrathecal morphine shot versus epidural morphine for controlling pain in women having elective cesarean delivery.
-
Using a number-based pain score plus a simple activity score to guide rescue pain medicine after surgery
This project will test whether using a combined numerical pain score and a simple Functional Activity Score to decide when to give rescue pain medicine helps adults recover after surgery.
-
Erector spinae plane block versus intrathecal morphine for recovery after cesarean
This will test whether a postoperative erector spinae plane (ESP) block or intrathecal morphine helps women recover better after an elective cesarean delivery.
-
Ultrasound-guided auricularis magnus nerve block to reduce pain after middle ear surgery
This study will test whether an ultrasound-guided auricularis magnus nerve block reduces postoperative pain and bleeding in adults having middle ear surgery.
-
Comparing nerve block and morphine for pain relief after hip surgery
This study tests whether a nerve block can provide the same pain relief as morphine for people recovering from hip surgery.
-
Comparing high and low dose pain relief methods after heart valve surgery
This study is testing whether a high or low dose of a new pain relief method can help patients after heart valve surgery feel less pain and use fewer opioids.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.