Using Vitamin B Complex for Pain Relief After Cesarean Section
The Analgesic Efficacy of Vitamin B Complex with Paracetamol and Non-steroidal Antiinflammatory Medication in Critically Ill Obstetrics After Caesarian Section; a Prospective Randomized , Placebo-controlled and Double-blinded Study
This study is testing if adding vitamin B complex to standard pain relief methods can help women recover better after a cesarean section while reducing the need for opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Sex | Female |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Egypt) |
| Trial ID | NCT06446830 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of vitamin B complex in enhancing pain relief for critically ill obstetric patients following cesarean sections, alongside a standard opioid-sparing multimodal analgesia regimen. The goal is to improve postoperative recovery while minimizing the side effects commonly associated with opioid use. By focusing on a multimodal approach, the study aims to promote better mobility, oral intake, and overall recovery for both the mother and infant. The research is particularly relevant given the unique challenges of pain management in obstetric care.
Who should consider this trial
Good fit: Ideal candidates are critically ill obstetric patients scheduled for cesarean delivery under neuraxial anesthesia.
Not a fit: Patients with known allergies to the components of the vitamin B complex or those with severe organ dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and recovery outcomes for mothers after cesarean sections.
How similar studies have performed: While the use of multimodal analgesia is well-established, the specific application of vitamin B complex in this context is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Critically ill -obstetric patients who will be delivered by cesarean section under neuraxial anesthesia. Exclusion Criteria: 1. Patient's Refusal to participate 2. Known allergy to one or more of the given components. 3. Disturbed conscious level. 4. Prolonged or complicated surgery; defined by operative time of more than 90 min. 5. Severe liver dysfunction or failure 6. Severe renal dysfunction or failure. 7. Severe thrombocytopenia; platelets less than 50
Where this trial is running
Cairo, Egypt
- Ain shams university — Cairo, Egypt, Egypt (Recruiting)
Study contacts
- Principal investigator: wessam selima, MD — assistant professor (lecturer)- Ain shams university
- Study coordinator: wessam selima, MD
- Email: w.z.selima@med.asu.edu.eg
- Phone: 01001958858
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.