Fixing large-angle outward eye turn with either muscle transplantation or Y-splitting recession
Comparative Study of Muscle Transplantation Versus Y Splitting Recession Technique in Treatment of Large Angle Exotropia
NA · Ain Shams University · NCT07350330
This trial will try two types of monocular eye-muscle surgery—muscle transplantation and Y-splitting recession—in people over 6 with large-angle exotropia (50–70 prism diopters).
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | Ain Shams University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07350330 on ClinicalTrials.gov |
What this trial studies
This interventional, single-center comparison tests two augmented recession techniques performed on one eye to correct large-angle exotropia: muscle transplantation versus Y-splitting recession. Eligible participants are older than 6 years with an exotropia angle of 50–70 prism diopters and may be myopic or hypermetropic. Key exclusions include prior strabismus surgery, significant vertical deviation, paralytic or restrictive squint, and any neurological disease. Surgeries and follow-up take place at Ain Shams University in Cairo with outcomes focused on ocular alignment and need for additional procedures.
Who should consider this trial
Good fit: Ideal candidates are people older than 6 years with large-angle exotropia (50–70 PD), with myopic or hypermetropic refraction and no prior strabismus surgery or significant vertical/incomitant issues.
Not a fit: Patients with previous squint surgery, significant vertical or incomitant deviations, paralytic or restrictive disorders, neurological disease, or exotropia angles outside 50–70 PD are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, one of the techniques could produce better alignment with fewer repeat surgeries, improving both vision function and cosmetic appearance.
How similar studies have performed: Both muscle transplantation and Y-splitting have been reported in surgical case series to help correct large-angle exotropia, but direct head-to-head comparative data are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age should be of more than 6 years Exotropia of an angle ranging from 50 to 70 PD Myopic or hypermetropic refraction Exclusion Criteria: * history of previous squint surgery significant vertical deviation incomitant squint in the form of paralytic or restrictive disorder any neurological disease
Where this trial is running
Cairo
- Ain shams university — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Alaa mohsen Elmaghraby, masters
- Email: Alaa.Mohsen@med.asu.edu.eg
- Phone: +201115538151
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Exotropia