Using Peripheral Perfusion Index to Predict Caudal Block Success in Kids Undergoing Surgery
Official title: Peripheral Perfusion Index as an Early Predictor of Successful Caudal Block in Pediatric Patients Undergoing Lower Abdominopelvic Surgeries Under General Anesthesia
Run by Ain Shams University · NCT06846983 · Data updated 2026-11-12
This study is testing if a special measurement called the peripheral perfusion index can help predict if a pain relief technique will work for young children having surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Year to 5 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Abbasia) |
| Status | Recruiting |
| Started | January 2, 2025 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | February 26, 2025 |
| Trial ID | NCT06846983 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pediatric patients aged 1-5 years scheduled for elective lower abdominopelvic surgeries under general anesthesia.
✕Probably not a fit
Patients with ASA physical status classes III or above, or those with certain neurological disorders or infections, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of the peripheral perfusion index (PPI) as an early predictor of successful caudal block in pediatric patients undergoing elective lower abdominopelvic surgeries under general anesthesia. Preoperative assessments will include a thorough medical history, clinical examination, and standard laboratory tests. Patients will be monitored during surgery using various methods, including pulse oximetry to measure PPI, which will be applied to the patient's toe. The study will focus on children aged 1-5 years and will adhere to strict preoperative fasting guidelines.
Why it matters
Potential benefit: If successful, this study could improve the predictability of caudal block effectiveness, leading to better pain management in pediatric surgeries.
How similar studies have gone: While the use of peripheral perfusion index in this context is relatively novel, similar studies have shown promise in improving anesthesia outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients aging between 1-5 years of both sexes. * Pediatric patients posted for elective lower abdominopelvic surgeries under general anesthesia (duration of surgery under 120 minutes). * ASA physical status classes I - II. Exclusion Criteria: * Guardian's refusal of procedure or participation in the study. * ASA classes III or above. * Infection at site of injection. * Neurological diseases and disorders such as (neuromuscular disease, cerebral palsy, spinal dysraphism …etc.) * Coagulopathy and bleeding disorders. * Hypersensitivity to the study medications. * Patients receiving vasoactive drugs or beta blockers. * Patients undergoing emergency surgery. * Patients in active clinical sepsis.
Where it's running
-
Ain Shams University
Cairo, Abbasia, Egypt Recruiting
Study contacts
- Study coordinator: Mohamed Khaled Mohamed Ahmed, M.B.B.CH., M.Sc.
- Email: mohamed.mohsen@med.asu.edu.eg
- Phone: +2001069123693
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Caudal Block for Distal Hypospadias Repair in Young Boys
This trial tests whether adding a caudal block to general anesthesia affects fistula formation after distal hypospadias repair in boys aged 6–60 months.
-
Sacral erector spinae plane block versus caudal epidural block for pain after hypospadias repair in young boys
This trial will see if a sacral erector spinae plane block or a caudal epidural block gives better pain relief for boys aged 1–5 after hypospadias repair.
-
NAVA use in preterm neonates with respiratory distress syndrome
This trial tests whether neurally adjusted ventilatory assist (NAVA) helps preterm babies with respiratory distress syndrome breathe more easily than conventional ventilation.
-
Ruta C and Vitamin C in Sepsis: Adding antioxidants to standard care
This trial tests whether adding Ruta C (rutin plus vitamin C) or vitamin C alone to standard sepsis treatment helps adults in the ICU stay shorter and recover better.
-
Left DLPFC rTMS vs iTBS for emotional dysregulation, impulsivity, and NSSI in Borderline Personality Disorder
This trial tests whether high-frequency rTMS or intermittent theta-burst stimulation over the left DLPFC can help reduce emotional instability, impulsivity, and non-suicidal self-injury in adults with Borderline Personality Disorder.
-
Trimetazidine as an extra therapy for aluminum phosphide poisoning
In this pilot trial, adults with acute aluminum phosphide poisoning receive standard care plus trimetazidine to see if it helps save lives and improve recovery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.