Restoring non-cavity dental lesions with different materials

Restoration of Non-carious Cervical Lesions: The Effect of Different Resin Composites Bonded With A Universal Adhesive Utilizing Two Adhesion Approaches: A Randomized Clinical Study

Not applicable Interventional Ain Shams University · NCT06393699

This study is testing different materials and methods to see which works best for treating non-cavity dental lesions in patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment52 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06393699 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of various resin composites and adhesive techniques in restoring non-carious cervical lesions (NCCLs) in patients. A total of 52 participants will have two NCCLs treated on opposite sides of their mouths, using either an etch-and-rinse or self-etching adhesive approach. The restorations will be monitored for retention and performance every six months over a two-year period. The goal is to determine which combination of materials and techniques yields the best clinical outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 with at least two non-carious cervical lesions in their premolars or canines.

Not a fit: Patients with medical conditions that interfere with dental care or those with periodontal disease in the target area may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the longevity and effectiveness of dental restorations for patients with non-carious cervical lesions.

How similar studies have performed: Previous studies have shown varying success with different adhesive approaches in dental restorations, making this a relevant investigation in the field.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Patients' age will range from 18 to 65 years.

* Presence of at least 2 NCCLs in one side.
* Patients with no medical condition could interfere with the routine dental care.
* Patients who will be able to attend for each recall visit.
* Patients with healthy periodontal tissues.
* Cavities presenting no more than 50% of margins in enamel.

Exclusion Criteria:

* Medically compromised patients.

  * Pregnant or breast-feeding patients.
  * Patients undergoing orthodontic treatment or bleaching treatment in the time of the study.
  * Patients with periodontal disease in the target area.
  * Patients presented with less than 20 teeth in the oral cavity.
  * Patients without antagonists.
  * Lesions superimposed with caries

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Retention
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.