Red Cell Distribution Width to Albumin Ratio in Burn Patients
Official title: Measurement of Red Cell Distribution Width/Albumin Ratio as a Predictive Tool for 30-day Mortality of Patients With Burn Injuries
Run by Ain Shams University · NCT07761845 · Data updated 2026-11-12
This observational study tests whether the ratio of red cell distribution width to albumin measured within 24 hours of admission can predict 30-day mortality in adults with burn injuries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | August 1, 2026 |
| Main results expected | February 1, 2027 |
| Study ends | April 1, 2027 |
| Registry record updated | August 18, 2026 |
| Trial ID | NCT07761845 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with burn injuries covering more than 20% TBSA, admitted to ICU within 24 hours, and with complete admission labs (RDW and albumin).
✕Probably not a fit
Patients without complete admission labs or with burns under 20% TBSA may not benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects data from adults with burn injuries to see if the RDW/albumin ratio measured within 24 hours of hospital arrival can predict 30-day mortality. It records patient characteristics, burn severity, and comorbidities, and follows standard burn resuscitation practices in the first 72 hours, including fluid management and monitoring. No specific intervention is tested beyond routine care and the prognostic value of the biomarker ratio. The study uses ICU patients admitted within 24 hours and relies on laboratory data obtained on admission to calculate the ratio and assess its association with 30-day outcomes.
Why it matters
Potential benefit: If the RDW/albumin ratio proves predictive, clinicians may better identify high-risk burn patients early and tailor monitoring and resources accordingly.
How similar studies have gone: Observational studies in critical illness have explored RDW and albumin as prognostic markers, but the specific RDW/albumin ratio in burn mortality prediction is less established and requires validation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years. * Both sexes. * Patients with burn injuries (%TBSA \>20%). * Availability of complete laboratory data (RDW, albumin) on admission. * Admission to ICU within 24 hours of burn injury. Exclusion Criteria: * Age \<18 years. * Patients with chronic hematologic disease. * Pre-existing liver disease. * Nephrotic syndrome. * patients on chemotherapy. * Patients with incomplete or missing lab records. * Pregnant females. * Patient or guardian refusal.
Where it's running
-
Ain shams university
Cairo, Cairo Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Ahlam M abdelnaby. study principal investigator, MBBCH, MSc .
- Email: g19-29502090100101@med.asu.edu.eg
- Phone: +201120327604
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.