Infraclavicular axillary vein collapsibility to predict who will respond to fluids in sepsis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study measures the infraclavicular axillary vein collapsibility index using ultrasound in spontaneously breathing adult patients with sepsis and clinical signs of acute circulatory failure. Investigators will compare the vein collapsibility measurements with patients' fluid responsiveness after fluid administration to determine predictive value. The protocol enrolls adults meeting at least two SIRS criteria and excludes mechanically ventilated patients and those under 18. The goal is to validate a noninvasive alternative to inferior vena cava measurements for guiding resuscitation decisions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients ≥18 years.
* Patients with sepsis must meet at least two or more criteria of systemic inflammatory response syndrome (SIRS).
* Spontaneously breathing patients.
* Clinical signs of acute circulatory failure.

Exclusion Criteria:

* Patients below the age of 18 years.
* Mechanically ventilated patients

Where it's running

• Ain-Shams University Hospitals
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Ibrahim Mamdouh Esmat
• Email: ibrahim_mamdouh@med.asu.edu.eg
• Phone: 01001241928

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.