Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 20 to 50

Effects of Healing Time on Bone Grafting After Tooth Extraction

Official title: Influence of Various Healing Intervals on Alveolar Ridge Preservation Using Demineralized Dentin Graft: A Randomized Clinical Trial

Run by Ain Shams University · NCT06031298 · Data updated 2026-11-12

This study is testing how waiting different amounts of time after a tooth extraction affects the success of a bone graft to help prepare for dental implants.

Quick facts

PhasePhase 4
Study typeInterventional
Ages20 Years to 50 Years
SexAll
Enrollment30 (estimated)
SponsorAin Shams University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedNovember 1, 2023
Main results expectedNovember 1, 2025
Study endsJanuary 1, 2026
Registry record updatedJanuary 31, 2025
Trial IDNCT06031298 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy adults aged 20 to 50 with non-molar maxillary teeth indicated for extraction and intact or minimally compromised bony walls.

Probably not a fit

Patients with acute infections, smokers, or those with uncontrolled systemic conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates how different healing intervals affect the success of demineralized dentin grafts used in alveolar ridge preservation after tooth extraction. Thirty patients with non-molar maxillary teeth requiring extraction will be randomly assigned to three groups, each receiving grafting at different time intervals. The study aims to determine the optimal timing for re-entry procedures to enhance bone healing and prepare for dental implants. Participants will be monitored for healing outcomes to assess the effectiveness of the grafting technique.

Why it matters

Potential benefit: If successful, this study could improve the outcomes of dental implant procedures by optimizing the timing of alveolar ridge preservation.

How similar studies have gone: Previous studies have shown promising results with similar grafting techniques, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Systemically free patients (American Society of Anesthesiologists I; ASA I)
* Age range 20 - 50.
* Non-molar maxillary teeth indicated for extraction.
* Patients with extraction sockets having intact bony walls, or no more than one bony wall dehiscence not extending more than 50% of the total bone height

Exclusion Criteria:

* Teeth to be extracted or adjacent teeth associated with acute infections.
* Smokers.
* Patients with other conditions that may affect the treatment \[uncontrolled diabetes mellitus (HbA1c \>7.0), liver or kidney failure, any active oral or systemic acute infections, currently receiving chemo-or radiotherapy or a history of radiotherapy in the head and neck area, severe hematologic disorders\].
* Pregnant and lactating females.
* Patients with history of lack of compliance to dental visits and unwillingness or inability to sign the informed consent.

Where it's running

  • Faculty of Dentistry - Ain Shams University
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.