Effects of Healing Time on Bone Grafting After Tooth Extraction
Influence of Various Healing Intervals on Alveolar Ridge Preservation Using Demineralized Dentin Graft: A Randomized Clinical Trial
This study is testing how waiting different amounts of time after a tooth extraction affects the success of a bone graft to help prepare for dental implants.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 20 Years to 50 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06031298 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how different healing intervals affect the success of demineralized dentin grafts used in alveolar ridge preservation after tooth extraction. Thirty patients with non-molar maxillary teeth requiring extraction will be randomly assigned to three groups, each receiving grafting at different time intervals. The study aims to determine the optimal timing for re-entry procedures to enhance bone healing and prepare for dental implants. Participants will be monitored for healing outcomes to assess the effectiveness of the grafting technique.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 20 to 50 with non-molar maxillary teeth indicated for extraction and intact or minimally compromised bony walls.
Not a fit: Patients with acute infections, smokers, or those with uncontrolled systemic conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the outcomes of dental implant procedures by optimizing the timing of alveolar ridge preservation.
How similar studies have performed: Previous studies have shown promising results with similar grafting techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Systemically free patients (American Society of Anesthesiologists I; ASA I) * Age range 20 - 50. * Non-molar maxillary teeth indicated for extraction. * Patients with extraction sockets having intact bony walls, or no more than one bony wall dehiscence not extending more than 50% of the total bone height Exclusion Criteria: * Teeth to be extracted or adjacent teeth associated with acute infections. * Smokers. * Patients with other conditions that may affect the treatment \[uncontrolled diabetes mellitus (HbA1c \>7.0), liver or kidney failure, any active oral or systemic acute infections, currently receiving chemo-or radiotherapy or a history of radiotherapy in the head and neck area, severe hematologic disorders\]. * Pregnant and lactating females. * Patients with history of lack of compliance to dental visits and unwillingness or inability to sign the informed consent.
Where this trial is running
Cairo
- Faculty of Dentistry - Ain Shams University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohamed A Mohamed
- Email: mohamed.mostafa@miuegypt.edu.eg
- Phone: +201224005098
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.