Comparing two types of nerve blocks for pain relief after breast surgery

Efficacy of Ultrasound Guided Pectoral Nerve Block Versus Ultrasound Guided Mid-point Transverse Process Block for Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy

NA · Ain Shams University · NCT06873893

This study is testing which of two types of nerve blocks can better relieve pain for women after breast surgery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages35 Years to 65 Years
SexFemale
SponsorAin Shams University (other)
Locations1 site (Cairo , Abbassya)
Trial IDNCT06873893 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of two different ultrasound-guided nerve blocks—pectoral nerve block and mid-point transverse process block—in providing postoperative analgesia for women undergoing modified radical mastectomy. Patients will undergo a thorough preoperative assessment, including medical history and laboratory tests, before being randomly assigned to one of the two nerve block techniques. The procedure will be performed by an experienced anesthesiologist under sterile conditions after the induction of general anesthesia. Pain levels will be monitored using a numeric rating scale to assess the effectiveness of each technique.

Who should consider this trial

Good fit: Ideal candidates are female patients aged 35 to 65 who are scheduled for modified radical mastectomy.

Not a fit: Patients who have contraindications for local anesthetic use or those with significant comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast surgery.

How similar studies have performed: Previous studies have shown varying success with nerve blocks for postoperative pain management, making this approach both relevant and potentially beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all female patients undergoing modified radical mastectomy
* age between 35 to 65

Exclusion Criteria:

* patient refusal of procedure or participation in the study
* duration of operation more than 180 minutes
* known ASA IV or more
* local skin infection at site of the block
* contraindication of local anesthetic infiltration ( history or evidence of coagulopathy , use of anticoagulant or antiplatelet therapy , known allergy of local anethestic (bupivacaine )

Where this trial is running

Cairo , Abbassya

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Post Operative Pain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.