Comparing dexmedetomidine and bupivacaine for pain management after brain surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of dexmedetomidine as an adjuvant to bupivacaine in scalp block versus bupivacaine alone for managing postoperative pain in patients undergoing craniotomy. The approach utilizes scalp block as a multimodal strategy to alleviate pain and reduce hemodynamic responses during surgery. By incorporating dexmedetomidine, a selective alpha-2 adrenergic receptor agonist, the study aims to enhance the analgesic effects and prolong the duration of action of local anesthetics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 65 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I or II.
* Undergoing supratentorial elective planned craniotomies.

Exclusion Criteria:

* Patients refusal.
* History of known allergy to the used local anesthetic or dexmedetomidine.
* Bleeding disorders.
* Evidence of local infection at the site of injection.
* Emergency craniotomy.
* Psychotic disorder.
* Patients who will not be extubated in the operating room after surgery.

Where it's running

• Ain Shams University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Omar A Khiralla, MBBCH
• Email: Omar-Ahmed@med.asu.edu.eg
• Phone: 00201095281838

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.