Comparing oral pregabalin and fentanyl for pain relief after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of preoperative oral pregabalin versus intraoperative intravenous fentanyl in managing postoperative pain for patients undergoing diagnostic laparoscopic gynecologic surgery. Patients will be randomly assigned to receive either pregabalin or a placebo before surgery, while the control group will receive fentanyl during the procedure. The goal is to assess the analgesic effects and opioid-sparing potential of pregabalin, which may lead to reduced side effects associated with opioid use. The study will involve 80 participants divided into two groups, each receiving different interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA physical status I

Exclusion Criteria:

* Patients' refusal
* use of sedatives, hypnotics, anti-psychotic or antidepressant drugs
* history of drug/alcohol abuse
* history of chronic pain
* daily intake of analgesics
* history of epilepsy

Where it's running

• Ain-Shams University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Ghada Mohamed Samir, MD
• Email: dr.ghada216@gmail.com
• Phone: 01005043691

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.