Nd:YAG Laser Plus Sclerotherapy vs Diode Laser Plus Sclerotherapy for Spider Veins and Reticular Veins

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two multimodal treatments for reticular veins and telangiectasias (spider veins) using the CLaCS technique. Participants receive either Nd:YAG laser with sclerosant injections or diode laser with sclerosant injections, followed by skin cooling to reduce pain and protect the skin. The trial assesses vein clearance and safety to determine which method provides better cosmetic results. Eligible adults aged 18-60 with C1 class veins and Fitzpatrick skin types II–V are recruited at Ain Shams University in Cairo, Egypt. The study aims to improve targeted vein visualization and treatment efficacy while maintaining tolerability.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-60 years.
* Both sexes.
* Presence of reticular veins and/or telangiectasias (CEAP classification C1).
* Fitzpatrick skin types II-V.
* Patients seeking cosmetic treatment.

Exclusion Criteria:

* Pregnancy or lactation.
* History of deep vein thrombosis.
* Coagulation disorders.
* Allergy to sclerosant agents.
* Active skin infection at treatment site.
* Previous treatment of target veins within 6 months.
* Great saphenous vein or short saphenous vein incompetence.
* Deep venous insufficiency or thrombosis.
* Abnormal venous duplex findings.

Where it's running

• Ain Shams University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed A Hagag, MD
• Email: hagagmohamed@med.asu.edu.eg
• Phone: 00201126560324

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.