Evaluating mortality predictors in head trauma patients

Predictors of Mortality Among Patients With Head Trauma

This study is trying to see if certain scoring systems can help doctors predict the chances of survival for patients with traumatic brain injuries in the ICU.

Quick facts

• Study type: Observational
• Enrollment: 140 (estimated)
• Ages: 16 Years to 75 Years
• Sex: All
• Sponsor: Ain Shams University (Academic / other)
• Locations: 1 site (Cairo)
• Trial ID: NCT06922396 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the effectiveness of various scoring systems, including APACHE II, RTS, and GCS, in predicting mortality among patients with traumatic brain injury (TBI) admitted to the intensive care unit (ICU). It will analyze factors such as age, sex, laboratory data, and complications to identify key predictors of outcomes. The study highlights the significant global burden of TBI, particularly in low- and middle-income countries, where mortality rates are notably higher. By understanding these predictors, the study seeks to improve clinical decision-making and patient management in critical care settings.

Who should consider this trial

Good fit: Ideal candidates include patients over 16 years old with acute traumatic brain injury presenting within 24 hours of trauma and a Glasgow Coma Scale score of less than 15.

Not a fit: Patients who have experienced cardiac arrest, have a GCS of 3, or have severe associated injuries or previous neurological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the ability to predict mortality in TBI patients, leading to improved treatment strategies and outcomes.

How similar studies have performed: Other studies have indicated the importance of scoring systems in predicting outcomes for TBI patients, suggesting that this approach has been validated in similar contexts.

Eligibility criteria

Inclusion Criteria:

* All patients with acute traumatic brain injury older than 16 years where presented in emergency department within 24 hours of trauma with a Glasgow coma scale less than 15

Exclusion Criteria:

* o Post cardiac arrest

  * Patients with GCS=3.
  * Patients with associated advanced cervical spine, maxillofacial, severe chest trauma.
  * Patients with previous neurological disorders

Where this trial is running

Cairo

• Faculty Of Medicine , Ain Shams University — Cairo, Egypt (Recruiting)

Study contacts

• Study coordinator: Ayman Mahmoud Alsayes, Master

Conditions The Usefulness of Specific Scores in Predicting Mortality of Patients With Head Trauma in ICU