Comparing two types of nerve blocks for pain relief after breast cancer surgery
Comparison Between Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy
This study is testing which of two nerve block techniques helps women have less pain after breast cancer surgery.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 21 Years to 65 Years |
| Sex | Female |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Waili) |
| Trial ID | NCT06947330 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness and safety of two regional anesthesia techniques, the Erector Spinae Plane Block (ESPB) and the Serratus Anterior Plane Block (SAPB), in providing analgesia for women undergoing modified radical mastectomy. Participants will be randomly assigned to receive one of the two blocks before surgery, and their pain levels will be monitored postoperatively for 24 hours. The study will also assess the risk of complications such as pneumothorax associated with each technique. The findings could provide valuable insights into optimizing pain management for breast surgery patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adult females aged 21 to 65 with ASA Physical Status II or III who are scheduled for a modified radical mastectomy.
Not a fit: Patients with severe comorbidities (ASA IV, V, VI), infections at the block site, or those on anticoagulants may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for women undergoing breast cancer surgery.
How similar studies have performed: There is limited literature comparing ESPB and SAPB in breast surgeries, indicating that this study may provide novel insights into their effectiveness.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA Physical Status II, or III. * Age 21 - 65 years. * Female gender Exclusion Criteria: * ASA IV, V, VI. * Infection at site of block. * Coagulopathy, or patients on antiplatelets, or anticoagulants. * Previous anesthetic allergy to bupivacaine. * Distant organ metastasis. * Male gender.
Where this trial is running
Cairo, Waili
- Faculty of Medicine, Ain-Shams University — Cairo, Waili, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.