Comparing two methods for closing the vaginal vault after laparoscopic hysterectomy
Official title: Laparoscopic Versus Transvaginal Closure of the Vaginal Vault After Total Laparoscopic Hysterectomy - a Single Blinded Randomized Comparative Study
Run by Ain Shams University · NCT06867614 · Data updated 2026-11-12
This study is testing two different ways to close the vaginal area after laparoscopic hysterectomy to see which method has fewer complications for women with benign uterine conditions.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | Women only |
| Enrollment | 48 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | January 14, 2025 |
| Main results expected | August 31, 2025 |
| Study ends | January 19, 2026 |
| Registry record updated | March 10, 2025 |
| Trial ID | NCT06867614 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult females with benign uterine conditions who are non-obese and sexually active.
✕Probably not a fit
Patients with pelvic malignancy, obesity, or conditions that impair wound healing will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare two techniques for closing the vaginal vault after total laparoscopic hysterectomy: laparoscopic closure and transvaginal closure. The study will assess the risk of complications such as vaginal vault hematoma, vaginal cuff infection, and sexual dysfunction associated with each technique. Adult females with benign uterine conditions who are non-obese and sexually active will be included in the trial. The findings could provide valuable insights into the safest and most effective closure method for patients undergoing this procedure.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for women undergoing total laparoscopic hysterectomy.
How similar studies have gone: While there may be existing studies on surgical techniques for hysterectomy, this specific comparison of closure methods is less commonly explored, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult females consenting to do TLH all age groups with diagnoses of benign uterine conditions. * Women who are non-obese (normal or overweight women with BMI range 18-29.9). * Sexually active female. Exclusion Criteria: * Diagnosed cases of pelvic malignancy * Diagnosed patients with Cervical intraepithelial neoplasia (CIN) or bacterial vaginosis (any infection should be treated) * Obese patients. * Patients currently undergoing treatment for any type of cancer * Patients with coagulopathy, bleeding/clotting disorders * Patients with any condition can impair wound healing: diabetes mellites, anemia, steroids * Patients with a previous history of radiation and allergy to sutures * Patients with clinically evident prolapse
Where it's running
-
Ain Shams University maternity hospital
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Rowan A Sakr
- Email: 150232@med.asu.edu.eg
- Phone: +201026141345
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.