Evaluating 3D Soft Tissue Simulation for Jaw Surgery
Official title: Segmented 3D Facial Conformation Meshes and Regional Esthetic Subunits: Advancing Soft Tissue Prediction Planning for Orthognathic Surgery: A Retrospective Study
Run by Ain Shams University · NCT06893614 · Data updated 2026-11-12
This study tests if using 3D imaging can help plan jaw surgery better for people with certain facial deformities.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 13 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Drugs / interventions | radiation |
| Locations | 2 sites (Cairo, Abbassia and 1 other locations) |
| Status | Recruiting |
| Started | March 12, 2025 |
| Main results expected | April 15, 2025 |
| Study ends | May 1, 2025 |
| Registry record updated | March 25, 2025 |
| Trial ID | NCT06893614 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with Class III dentofacial deformities who have undergone bimaxillary orthognathic surgery and have preoperative and at least 6 months postoperative CBCT scans available.
✕Probably not a fit
Patients with craniofacial anomalies, previous maxillofacial surgeries, or significant facial asymmetry may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study conducts a retrospective analysis of existing Cone Beam Computed Tomography (CBCT) scans from patients who underwent bimaxillary orthognathic surgery for Class III dentofacial deformities. It aims to assess the accuracy of 3D soft tissue predictions using advanced imaging techniques and software. By integrating segmented 3D facial meshes and analyzing various facial regions, the study seeks to enhance the precision of surgical planning and outcomes. The methodology includes voxel-based registration and color-coded error maps to visualize prediction accuracy.
Why it matters
Potential benefit: If successful, this study could significantly improve the accuracy of soft tissue predictions in orthognathic surgery, leading to better surgical outcomes for patients.
How similar studies have gone: Other studies utilizing 3D imaging and soft tissue prediction models have shown promising results, indicating that this approach is both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preoperative and at least 6 months postoperative CBCTs of Patients who suffered from class III facial deformity and had bimaxillary orthognathic surgical correction who undergone maxillary advancement and mandibular setbacks. Exclusion Criteria: * CBCTs of patients with: * Craniofacial anomalies including cleft lip/palate, * who had had previous maxillofacial operations or facial scars, * Surgical Corrections that required multi-segment Le Fort I osteotomies, * Simultaneous Genioplasty as part of the carried-out corrections. * Significant facial Asymmetry. * Missing Data
Where it's running
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Ain Shams University
Cairo, Abbassia, Egypt Recruiting -
Ain Shams University
Abbassia, Cairo Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Nehal I Shobair, Lecturer — Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Misr International University, Cairo, Egypt
- Study coordinator: Nehal I Shobair, PhD
- Email: nehal.shobair@miuegypt.edu.eg
- Phone: +201063666985
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Hunsuck vs Posnick Medial Mandibular Osteotomy Modifications and Postoperative Stability
This study tests whether the Hunsuck or Posnick modification used during jaw surgery helps keep the lower jaw in place after the procedure.
-
How the upper jaw bone segment is positioned during jaw surgery affects jaw joint remodeling
This study tests whether rotating or leveling the proximal segment during bimaxillary orthognathic surgery changes how the condyle remodels after surgery in adults with skeletal Class III deformities.
-
Using a 3D-printed jaw model to improve understanding before orthognathic surgery
This test will see if giving adults scheduled for double- or triple-jaw surgery a 3D-printed model of their jaw helps them understand the procedure better, lowers preoperative anxiety, and increases satisfaction compared with standard 2D explanations.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.