Evaluating 3D Soft Tissue Simulation for Jaw Surgery

Segmented 3D Facial Conformation Meshes and Regional Esthetic Subunits: Advancing Soft Tissue Prediction Planning for Orthognathic Surgery: A Retrospective Study

Observational Ain Shams University · NCT06893614

This study tests if using 3D imaging can help plan jaw surgery better for people with certain facial deformities.

Quick facts

Study typeObservational
Enrollment13 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorAin Shams University Academic / other
Drugs / interventionsradiation
Locations2 sites (Cairo, Abbassia and 1 other locations)
Trial IDNCT06893614 on ClinicalTrials.gov

What this trial studies

This observational study conducts a retrospective analysis of existing Cone Beam Computed Tomography (CBCT) scans from patients who underwent bimaxillary orthognathic surgery for Class III dentofacial deformities. It aims to assess the accuracy of 3D soft tissue predictions using advanced imaging techniques and software. By integrating segmented 3D facial meshes and analyzing various facial regions, the study seeks to enhance the precision of surgical planning and outcomes. The methodology includes voxel-based registration and color-coded error maps to visualize prediction accuracy.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with Class III dentofacial deformities who have undergone bimaxillary orthognathic surgery and have preoperative and at least 6 months postoperative CBCT scans available.

Not a fit: Patients with craniofacial anomalies, previous maxillofacial surgeries, or significant facial asymmetry may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve the accuracy of soft tissue predictions in orthognathic surgery, leading to better surgical outcomes for patients.

How similar studies have performed: Other studies utilizing 3D imaging and soft tissue prediction models have shown promising results, indicating that this approach is both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Preoperative and at least 6 months postoperative CBCTs of Patients who suffered from class III facial deformity and had bimaxillary orthognathic surgical correction who undergone maxillary advancement and mandibular setbacks.

Exclusion Criteria:

* CBCTs of patients with:

  * Craniofacial anomalies including cleft lip/palate,
  * who had had previous maxillofacial operations or facial scars,
  * Surgical Corrections that required multi-segment Le Fort I osteotomies,
  * Simultaneous Genioplasty as part of the carried-out corrections.
  * Significant facial Asymmetry.
  * Missing Data

Where this trial is running

Cairo, Abbassia and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Orthognathic Surgical ProceduresOrthognathic SurgeryThree-Dimensional Imaging.Soft Tissue.Cone-Beam Computed TomographyPrognathismTreatment OutcomeComputer Simulation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.