Impact of a Parasternal Intercostal Block on Internal Thoracic Artery Harvest in CABG
Official title: Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG
Run by Ain Shams University · NCT07663435 · Data updated 2026-11-12
This study tests whether a superficial parasternal intercostal plane block can improve the ITA caliber and help surgeons harvest the graft during CABG.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 22 Years to 65 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | July 1, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | October 28, 2026 |
| Trial ID | NCT07663435 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 22 to 65 undergoing CABG with IMA graft harvesting and able to provide consent.
✕Probably not a fit
Patients with active infection, uncontrolled hemodynamics, severe pulmonary disease, prior thoracic surgery, or other high-risk exclusions may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional Phase 3 trial tests the effect of a superficial parasternal intercostal plane block using bupivacaine on the caliber of the internal thoracic artery and the efficiency of graft harvesting in adults undergoing CABG. The approach aims to provide postoperative pain relief and may promote better ITA perfusion by reducing vascular resistance and increasing local blood flow in the early postoperative period. Participants are adults 22–65 undergoing CABG with IMA harvesting, without active infection, consent, or other major exclusion criteria. The study is conducted at Ain Shams University in Cairo under a lead sponsorship by Ain Shams University.
Why it matters
Potential benefit: If successful, patients could experience easier graft harvesting and potentially improved ITA blood flow during the critical perioperative period.
How similar studies have gone: Prior studies of regional parasternal blocks have shown analgesic benefits; this specific approach to ITA caliber and graft harvest is exploring a new application with uncertain outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Age group: Adult patients from age of 22 to 65 years. * Sex: Both sexes * Patients undergoing CABG with IMA harvesting Exclusion Criteria: * • Patients with pre-existing active bloodstream infection or systemic infection * Refuse consent * IMA graft not suitable * Morbidly obese (BMI \> 40 ) * Hemodynamic instability * Severe pulmonary disease * Previous thoracic surgeries (makes it difficult to harvest IMA) * Advanced malignancy or chronic disease with life expectancy less than six months * Emergency surgery
Where it's running
-
Faculty of Medicine ,Ain Shams University
Cairo, Cairo Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Sarah H Elghareeb, MD — Ain Shams
- Study coordinator: Sarah hamdy Elghareeb, MD
- Email: sarahhamdy@med.asu.edu.eg
- Phone: +201012434690
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.