Clinical trial Recruiting at 1 site Phase 3 Interventional Ages 22 to 65

Impact of a Parasternal Intercostal Block on Internal Thoracic Artery Harvest in CABG

Official title: Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG

Run by Ain Shams University · NCT07663435 · Data updated 2026-11-12

This study tests whether a superficial parasternal intercostal plane block can improve the ITA caliber and help surgeons harvest the graft during CABG.

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Quick facts

PhasePhase 3
Study typeInterventional
Ages22 Years to 65 Years
SexAll
Enrollment50 (estimated)
SponsorAin Shams University
Academic / other
Locations1 site (Cairo, Cairo Governorate)
StatusRecruiting
StartedJuly 1, 2026
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedOctober 28, 2026
Trial IDNCT07663435 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 22 to 65 undergoing CABG with IMA graft harvesting and able to provide consent.

Probably not a fit

Patients with active infection, uncontrolled hemodynamics, severe pulmonary disease, prior thoracic surgery, or other high-risk exclusions may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional Phase 3 trial tests the effect of a superficial parasternal intercostal plane block using bupivacaine on the caliber of the internal thoracic artery and the efficiency of graft harvesting in adults undergoing CABG. The approach aims to provide postoperative pain relief and may promote better ITA perfusion by reducing vascular resistance and increasing local blood flow in the early postoperative period. Participants are adults 22–65 undergoing CABG with IMA harvesting, without active infection, consent, or other major exclusion criteria. The study is conducted at Ain Shams University in Cairo under a lead sponsorship by Ain Shams University.

Why it matters

Potential benefit: If successful, patients could experience easier graft harvesting and potentially improved ITA blood flow during the critical perioperative period.

How similar studies have gone: Prior studies of regional parasternal blocks have shown analgesic benefits; this specific approach to ITA caliber and graft harvest is exploring a new application with uncertain outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Age group: Adult patients from age of 22 to 65 years.

  * Sex: Both sexes
  * Patients undergoing CABG with IMA harvesting

Exclusion Criteria:

* • Patients with pre-existing active bloodstream infection or systemic infection

  * Refuse consent
  * IMA graft not suitable
  * Morbidly obese (BMI \> 40 )
  * Hemodynamic instability
  * Severe pulmonary disease
  * Previous thoracic surgeries (makes it difficult to harvest IMA)
  * Advanced malignancy or chronic disease with life expectancy less than six months
  * Emergency surgery

Where it's running

  • Faculty of Medicine ,Ain Shams University
    Cairo, Cairo Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.