Papillary vs non-papillary access during PCNL
Official title: Evaluation of Safety and Efficacy of Papillary Versus NonPapillary Access During Percutaneous Nephrolithotomy: A Prospective Randomized Study
Run by Ain Shams University · NCT07855354 · Data updated 2026-11-12
This trial tests whether non-papillary renal access is a safe and effective alternative to the standard papillary approach during percutaneous nephrolithotomy in adults with kidney stones.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | November 1, 2025 |
| Main results expected | October 30, 2026 |
| Study ends | October 30, 2026 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT07855354 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older with solitary or multiple renal stones ≥2 cm who are candidates for PCNL.
✕Probably not a fit
Patients with anatomy or conditions that favor papillary access or those at high risk for non-papillary techniques may derive no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two access techniques for percutaneous nephrolithotomy: papillary puncture and non-papillary puncture. It aims to evaluate safety, efficacy, and clinical outcomes to determine if non-papillary access can be a viable option in selected patients. Eligible participants are adults with kidney stones of 2 cm or larger, suitable for PCNL, and without conditions that increase surgical risk. The study is conducted at Ain Shams University in Cairo and compares tract creation and complication rates between the two approaches.
Why it matters
Potential benefit: If successful, non-papillary access could expand surgical options and potentially reduce complications for certain patients.
How similar studies have gone: Prior data on non-papillary access are limited; this study seeks to add evidence on its safety and effectiveness.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Solitary or multiple renal calculi ≥2 cm * Ability to provide informed consent Exclusion Criteria: * Bleeding diathesis or uncorrected coagulopathy * Active urinary tract infection at the time of surgery * Congenital anomalies severely distorting renal anatomy (e.g., horseshoe kidney, ectopic kidney) * Morbid obesity \[body mass index (BMI) ≥ 40\] limiting safe positioning * Pregnancy
Where it's running
-
Ain Shams University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Mohamed I El-Sayed, MBBCH
- Email: 29709041800133@med.asu.edu.eg
- Phone: 00201068569307
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.