Sponsor or institution
Clinical trials and research at University of Alabama at Birmingham
As of November 12, 2026, Find a Trial lists 200 clinical trials run by University of Alabama at Birmingham that are recruiting, at sites in 16 countries (most in United States (190), Zambia (4), Brazil (2)). By phase: Phase 2 (18), Early Phase 1 (11), Phase 1 (10), Phase 4 (8). There are also 1,232 NIH-funded research projects at this institution, with $690.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 200Clinical trials
- 1232NIH research projects
- 16Countries
Newest trials
All recruiting trials (newest 150 of 200)
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Sleep Better, Live Better: a 12-week coaching program to help adults improve sleep and heart-brain health
This trial tests a 12-week, telephone- and text-based sleep coaching program for adults 25–65 with short sleep and higher cardiometabolic risk to see if it improves sleep and related behaviors.
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Community health worker support to lower blood pressure after pregnancy with high blood pressure
Postpartum patients with high blood pressure after pregnancy will try a program where a trained community health worker helps them monitor blood pressure and manage care for 6 months to see if it lowers blood pressure compared with usual care.
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Improving Care for underserved older Black patients with cardiovascular and other chronic conditions
This study tests a culturally tailored approach to patient-centered care for older African American patients with cardiovascular disease and other conditions who receive care at a community hospital.
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See if deep brain stimulation for Parkinson's changes thinking and movement and affects fall risk
This pilot study tests whether deep brain stimulation in people with Parkinson’s changes thinking or movement and whether those changes relate to how often they fall.
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Finance-focused psycho-oncology support for cancer patients experiencing financial hardship
This pilot tests whether two monthly 60-minute finance-focused counseling sessions over three months can help cancer patients who are experiencing financial distress.
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Nutrition education before arthroscopic knee or shoulder surgery
This study tests whether watching a nutrition education video before arthroscopic knee or shoulder surgery helps patients’ recovery by comparing those who viewed the video to those who did not.
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INSPIRE: Putting patient-reported info into multidisciplinary tumor boards
This study tests whether adding electronic patient-reported outcomes to tumor board discussions can help guide treatment decisions for women with breast, gynecologic, pancreatic cancers and related cancers.
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Yoga breathing and meditation program for people with spinal cord disorders
A virtual 8‑week program uses yogic breathing and meditation to see if it improves breathing, fatigue, mood, and quality of life for adults with spinal cord disorders.
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Acellular Dermal Matrix vs. Resorbable Collagen Barrier for Guided Bone Regeneration
This study compares an acellular dermal matrix barrier to a resorbable collagen membrane to see which works better for building width in horizontal ridge augmentation before implants.
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Hepatitis B in Zambia: an observational cohort of adults with HBV, with or without HIV
This observational cohort follows adults diagnosed with hepatitis B in Zambia, with and without HIV coinfection, to see how their liver disease and HBV (and HIV when present) change over several years while they receive standard care.
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False vocal fold Botox vs EMG-guided Botox for vocal tremor
This study tests whether injecting botulinum toxin into the false vocal fold is as good as the standard EMG-guided injection for people with essential vocal tremor.
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Ear vagus nerve stimulation to improve heart rate and blood pressure control in Parkinson's disease
This study will see if gentle ear-based vagus nerve stimulation can help people with Parkinson's disease better control their heart rate and blood pressure.
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Effects of exogenous ketones on brain energy and thinking in older adults with prediabetes
In older adults with prediabetes, researchers will test if a single dose of a ketone supplement can boost brain energy use and processing speed compared with people with normal blood sugar.
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Cognitive rehabilitation for ME/CFS brain fog
Researchers are testing two cognitive rehabilitation approaches to see which helps adults with ME/CFS and brain fog better manage thinking and daily tasks.
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Long-acting HIV PrEP and contraception PK study in AGYW
This study tests how long-acting cabotegravir for PrEP interacts with hormonal contraception in young women.
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Breath-Body-Mind for Young Breast Cancer Survivors with Psychological Distress
This study tests a breath-based group program to help younger breast cancer survivors on endocrine therapy see if it can ease psychological distress compared with a survivorship education program.
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Bundled telehealth, peer support, and buprenorphine after ED discharge to prevent opioid overdoses
This trial tests a bundled approach with telehealth, peer support, buprenorphine, and care linkage to see if it helps people who have overdosed and were discharged from the ED continue treatment and avoid repeat overdoses.
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Impact of meal timing on neurological health in adults with multiple sclerosis
This study tests whether eating within an 8-hour daily window or over a longer 12+ hour period affects brain health markers and inflammation in adults with MS.
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Process-Based Approach for Anxiety Problems (case series)
This case-series tests a process-based therapy for anxiety by creating personalized process networks to guide up to 25 counseling sessions for adults with anxiety.
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High-energy DHA/ARA-enriched human milk in the first 2 weeks to lower lung problems in extremely preterm babies
This trial tests whether giving DHA/ARA-enriched, fortified human milk in the first 14 days after birth helps extremely preterm infants breathe easier and have better lung function.
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Digital PrEP Toolkit to help cisgender women in the Southeast access PrEP
A Digital PrEP Toolkit is being tested to see if it helps cisgender women in Alabama and Mississippi learn about PrEP and start using it.
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VENTURI — Ventilation imaging comparing two triple-inhaler treatments for uncontrolled asthma
This trial tests two triple-combination inhalers to see which delivers medication better to the large and small airways in adults with uncontrolled asthma.
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Oncology financial navigation offered as part of routine care
This project will try offering financial navigation as part of routine cancer care at UAB to see if it reduces patients' financial hardship and improves quality of life and distress.
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Epidemiology and care for dialysis in ICU patients with severe acute kidney injury in Latin America
This project will collect and compare data on adults in ICUs across Latin America who need dialysis for severe acute kidney injury to see how they are treated and what outcomes they have.
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Using near-infrared ICG dye to check bile flow in newborns with cholestasis
We will give eligible newborns a single IV dose of indocyanine green (ICG) to see if the dye appears in their diapers, which would indicate bile is flowing and the bile ducts are open.
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PrEP Optimization Through Enhanced Continuum Tracking (PrOTECT AL)
This project will test a real-time PrEP care dashboard and implementation strategies at seven Alabama clinics to see if they increase PrEP coverage and equity among people at risk for HIV.
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Vevye eye drops for meibomian gland dysfunction in adults
This study tests whether Vevye eye drops (cyclosporine 0.1%) help adults with meibomian gland dysfunction who have dry, irritated eyes.
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Tinted daily contact lenses for light sensitivity after a concussion
This project will try daily disposable tinted contact lenses to reduce light sensitivity in adults who have had a mild concussion.
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Boosting Smell Training in Adults with HIV
This study tests two at-home smell-training methods to see if they improve scent function and thinking skills in adults with HIV.
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FELLAship program to improve heart and metabolic health in Black men
This program will try a 24-week, church-based combination of exercise and health education to see if it improves blood pressure, cholesterol, blood sugar, and weight for Black men age 18 and older in the Birmingham area.
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LEGAL-CARE: legal navigation to improve access to cancer care
This pilot tests a legal navigation program to help adults newly diagnosed with advanced (stage III/IV) cancer overcome legal, insurance, and financial barriers during their treatment.
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Comparing EDTA, chlorhexidine, and essential-oil mouthrinses after a tooth extraction with socket bone graft
This will test whether EDTA-based mouthrinses work as well as standard 0.12% chlorhexidine and an essential-oil rinse for immediate post-operative and daily use after a single-tooth extraction and ridge-preservation graft.
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Spinal cord stimulator effects on restless legs
This study will test whether changing spinal cord stimulator settings alters nerve signals and improves symptoms in people with restless leg syndrome and in some people with chronic pain.
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Cocoa with exercise to boost walking and strength in older adults
This study will test whether taking a cocoa supplement high in (-)-epicatechin together with regular aerobic and resistance exercise helps older adults with slow walking speed improve walking and muscle strength more than exercise alone.
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Early time-restricted eating for older adults with high blood pressure
This project will try early time-restricted eating in adults 60 and older with high blood pressure to see if a shorter, earlier daily eating window improves body rhythms and cardiovascular and metabolic health.
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How pneumococcal conjugate vaccines may produce antibodies that protect against serogroup 33.
This will try two different pneumococcal conjugate vaccines in healthy adults to see which one makes antibodies that can kill serogroup 33 bacteria.
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IgG genetic differences in people with alpha-1 antitrypsin deficiency
This study will test whether adults who carry one SERPINA1 Z mutation and have frequent COPD exacerbations make weaker antibody responses to the 20-valent pneumococcal vaccine than similar people without recent exacerbations.
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Transcutaneous Vagal Nerve Stimulation to help with brain vessel narrowing after aneurysm rupture
This trial tests whether using a noninvasive nerve stimulation device can reduce cerebral vasospasm after an aneurysmal brain bleed in adults 18–65 who are undergoing standard treatment.
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Initial testing of an educational approach to genetic services for families at risk of Lynch syndrome
This pilot study tests whether an information letter alone or with a booklet helps at-risk relatives decide about pursuing genetic services for Lynch syndrome.
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Comparing border saw and reciprocating saw for lower jaw osteotomy
This will see if using a border saw versus a reciprocating saw when making the lower jaw cut changes the pattern of inner bone breaks in people having mandibular surgery.
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Offering multiple PrEP options, including the dapivirine ring, to young women at reproductive health clinics
This program will try offering both daily oral PrEP and the dapivirine vaginal ring to women aged 18–30 who come for reproductive health services to see if more start and keep using HIV prevention.
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Exogenous ketone monoester effects on thinking, sensorimotor skills, and driving
This test will try a single dose of a ketone monoester supplement versus a placebo to see if it improves thinking, sensorimotor skills, and driving performance in adults 19–55 who are obese and sedentary, lean and sedentary, or lean and regularly active.
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Adding decitabine and venetoclax to fludarabine/melphalan reduced‑intensity transplant for myeloid cancers
This study tests whether giving decitabine and venetoclax around a reduced‑intensity allogeneic transplant is safe for adults with high‑risk acute myeloid leukemia or myelodysplastic syndromes.
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Better diabetes care for people with physical disabilities using telehealth in primary care
This study tests two telehealth approaches—digital health coaching and remote patient monitoring—to see which helps adults with type 2 diabetes and a physical disability control blood sugar and feel better about their care.
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ARISE: Upright bed positioning for acute respiratory distress syndrome
This pilot trial will test whether daily upright bed positioning helps adults hospitalized with acute respiratory distress syndrome compared with standard head-of-bed elevation.
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Best timing for a midurethral sling during robotic pelvic organ prolapse repair
This trial will test whether placing a midurethral sling before or after robotic sacrocolpopexy works better for women with stress urinary incontinence and pelvic organ prolapse.
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Investigating oxalate production in patients with calcium oxalate kidney stones
This study is testing if people with calcium oxalate kidney stones produce more oxalate in their bodies than healthy individuals by following a special diet and taking certain supplements.
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Inspire HER: a heart-health and stress-support program for Black women
This project will test whether the Inspire HER lifestyle program helps Black women with higher heart disease risk improve heart health and manage stress.
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Using a genetic blood-pressure risk score to guide care for adults with high blood pressure
This trial will test whether giving adults aged 18–55 with hypertension and poor cardiovascular health their genetic risk score for systolic blood pressure plus structured genomic counseling helps them lower blood pressure and improve healthy habits over 12 months.
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Genetic testing for personalized medication in stroke patients
This study is testing if using genetic testing can help doctors choose the best medication for stroke patients to improve their treatment and recovery.
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Brief online activities to change mood and attitudes in people with psychotic disorders and healthy adults
This project will try short online activities to see if they can improve mood and attitudes for adults with psychotic disorders and for healthy adults.
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Oral tranexamic acid after total shoulder replacement to reduce bleeding and help early recovery.
This Phase 3 study will test whether taking oral tranexamic acid after a total shoulder replacement helps adults 18–79 have less bleeding and better short-term recovery compared with a placebo.
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Low-carb diet to treat Type 2 diabetes in teens.
This 24-week test will see if a low-carb diet helps control blood sugar and improve insulin function in teens (ages 12–18) with Type 2 diabetes who are not using insulin.
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Healthy eating and physical activity support for cancer survivors and their families
This program will try a community-adapted healthy eating and physical activity support for adult cancer survivors and their family or friends living in persistent poverty in the Birmingham area.
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Comparing radiation margins in treating brain metastases with radiosurgery
This study is testing whether using different amounts of space around brain tumors during radiation treatment can help control the tumors better and reduce side effects for patients with brain metastases.
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Predicting and stopping breathing pauses in very preterm babies with gentle vibration
This study tests a vibro-tactile device to see if it can predict and prevent apnea with bradycardia in preterm infants by briefly stimulating them during episodes.
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Daily bright-light glasses to improve sleep and recovery in people with opioid use disorder
This trial will test whether wearing AYO bright-light glasses each morning can improve sleep patterns and support recovery in adults receiving medication for opioid use disorder.
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Using metformin to improve immune function in people with a history of injection drug use
This study is testing if the diabetes drug metformin can help improve the immune system and reduce inflammation in people aged 18-64 who have a history of using injection drugs.
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Stress-management program to reduce heart disease risk in women with HIV
This program will test whether the SMART stress-management intervention can lower blood pressure and other heart-disease risks for women living with HIV in the Southern US.
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Optimizing extended care to help people keep weight off
This program will test which combination of four low‑burden supports helps adults with obesity who have lost weight keep that weight off.
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Improving sleep quality in individuals with Down syndrome
This study is testing a new online program to help young people with Down syndrome sleep better and feel happier in their daily lives.
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Continuous vital signs monitoring using a consumer wearable in Ghana hospitals
This study tests whether a consumer wearable (Garmin Venu 3) can be used to continuously track heart rate, oxygen saturation, and breathing in pediatric trauma and post-appendectomy patients to catch deterioration earlier.
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Ketogenic versus low-fat diets to help keep weight off and change energy use and appetite
This tests whether a ketogenic diet versus an isocaloric low-fat diet helps people with obesity keep weight off by increasing daily energy use and reducing appetite.
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Folic Acid–Fortified Salt for Women of Reproductive Age in Zambia
This study tests whether iodized salt fortified with folic acid can raise blood folate levels in non-pregnant, non-lactating women in Zambia who don’t have a folic acid fortification program.
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Telehealth program to help Latinas prepare for urogynecologic surgery
This study is testing a telehealth program to help Latina women get ready for urogynecologic surgery and see if it makes the process easier for them.
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Comparing two types of intramedullary nails for healing tibial fractures
This study is testing whether a new type of tibial nail helps people with stable tibial fractures heal better and recover faster than the standard nail.
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Pumping schedule to boost breast milk for parents of very preterm infants
This will test whether pumping every 2 hours or every 3 hours helps parents of very preterm infants produce more breast milk during the baby’s first 28 days.
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Using Misoprostol to Prevent Cervical Cancer
This study is testing if the medication Misoprostol can help prevent cervical cancer in women who are being screened for the disease.
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Using Acceptance and Commitment Therapy to help religious OCD
This project will try Acceptance and Commitment Therapy (ACT) to see if it helps adults with religiously focused OCD.
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Coach-led caregiver program to boost early learning and literacy
This program will test whether adding coach-led caregiver training in early literacy and numeracy to regular shared reading helps term and late preterm infants have better developmental scores at 24 months.
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AI-based glaucoma and eye disease screening at federally qualified health centers
This project will test whether an AI-assisted eye screening program at federally qualified health centers can find glaucoma and other eye problems (like diabetic retinopathy and cataracts) and whether people follow up with an eye doctor.
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Using continuous glucose monitoring to manage type 2 diabetes during pregnancy
This study is testing whether using continuous glucose monitoring can help pregnant people with type 2 diabetes manage their blood sugar better than traditional self-monitoring methods.
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Counseling for LGBTQ+ individuals to reduce minority stress
This study is testing whether a special type of counseling can help LGBTQ+ individuals feel less stressed and improve their mental health compared to regular counseling.
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MIGHT — IVIG for anti‑HMGCR immune‑mediated necrotizing myopathy
This will test whether intravenous immunoglobulin (IVIG) helps people aged 16 and older with active anti‑HMGCR immune‑mediated necrotizing myopathy.
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Wearing special contact lenses to slow nearsightedness in children
This study is testing if special contact lenses can help slow down nearsightedness in children over the course of a year.
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Retraining and Control Therapy for adults with non-epileptic seizures
This study is testing a new therapy called Retraining and Control Therapy to see if it can help adults with non-epileptic seizures feel more in control and reduce their worries about their symptoms.
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Extended Kangaroo Mother Care for Mothers of Low Birthweight Infants
This study tests if staying longer in a special Kangaroo Mother Care ward can help mothers of low birthweight babies feel less depressed after giving birth.
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Improving gout care after emergency department visits
This study is testing a new way to help people with gout get better follow-up care after visiting the emergency room, especially for those in underserved communities in the Southeastern U.S.
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Caffeine citrate after discharge for moderately preterm infants at risk of apnea
This trial tests whether continuing caffeine citrate after hospital discharge reduces apnea-related healthcare visits and improves development at 12 months in moderately preterm infants, compared to a placebo.
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Adjusting ventilator PEEP to improve lung compliance and heart function in preterm infants
We will try changing the ventilator's PEEP settings in babies born before 34 weeks who need breathing support to see if the PEEP that gives the best lung compliance improves heart output and oxygen levels.
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Combination therapy to shrink plexiform neurofibromas in NF1 patients
This trial tests whether the drugs cabozantinib and selumetinib can be safely given together to see if they help shrink progressive or painful plexiform neurofibromas in adolescents and adults with NF1.
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Early time-restricted eating to support postpartum weight loss
This program will test whether an early time-restricted eating schedule helps postpartum women with overweight or obesity lose weight and is acceptable for them.
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Improving COVID-19 vaccine uptake in Black and Latinx patients with rheumatologic diseases
This study is testing a new approach to help Black and Latinx patients with autoimmune diseases get updated COVID-19 vaccines by providing them with helpful information and support.
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Improving outcomes for patients with fragility fractures
This study is testing if a new support program for older adults with recent bone fractures can help them recover better than standard care that just provides education.
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Effect of human milk diets on growth in preterm infants
This study is testing if giving moderately preterm infants more human milk can help them grow better without causing any health issues.
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Comparing higher versus lower oxygen targets for very preterm infants with BPD-related pulmonary hypertension
This trial will see if keeping very preterm infants with bronchopulmonary dysplasia and pulmonary hypertension at a slightly higher oxygen saturation (95–98%) versus a lower saturation (92–95%) helps them do better.
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HEAT telemedicine program for HIV and addiction care
This project will try a telemedicine program to deliver addiction treatment to adults living with HIV in Alabama who report opioid or stimulant misuse.
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Dual versus single immunotherapy combined with chemotherapy for PD-L1–negative advanced non-small cell lung cancer
This trial tests whether giving two immune checkpoint inhibitors plus chemotherapy works better than one immune checkpoint inhibitor plus chemotherapy for adults with stage IV, PD-L1–negative non-small cell lung cancer.
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Creating a treatment program for functional neurological disorder
This study is trying to create a new treatment plan for people with functional neurological disorder by bringing together different types of therapy to see if it helps both kids and adults feel better.
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Adapting Enhanced Recovery Programs for Low Health Literacy Patients
This study tests a multi-level VISACT approach to tailor enhanced recovery programs for adults undergoing surgery who have low health literacy.
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Cognitive training for preterm infants using finger puppets
This study is testing if using finger puppets in caregiver interactions can help preterm infants develop better communication skills compared to regular care.
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Investigating how the gut absorbs oxalate in kidney stone patients
This study is trying to see if people with kidney stones absorb more oxalate from their diet than healthy individuals, which might lead to more oxalate in their urine.
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Using gut bacteria to reduce urinary oxalate in kidney stone patients
This study is testing if introducing a specific gut bacteria can help adults with calcium oxalate kidney stones lower the amount of oxalate in their urine.
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Evaluating Siplizumab for Hidradenitis Suppurativa Treatment
This study is testing whether a new medication called siplizumab can help people with moderate to severe Hidradenitis Suppurativa who haven't found relief with other treatments.
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Two-step ATG to prevent GVHD after myeloablative allogeneic stem cell transplant
This study tests whether a two-step dosing of rabbit ATG added to tacrolimus and low-dose methotrexate can help prevent severe acute and chronic GVHD in adults 18–60 receiving myeloablative allogeneic peripheral blood stem cell transplants for leukemia, MDS, or myeloproliferative disorders.
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Comparing timing of gum grafts and bone regeneration for dental implants
This study is testing whether doing gum surgery before or after bone treatment helps dental implants heal better and have fewer problems.
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HydroMARK Plus versus HydroMARK: comparing biopsy site marker retrieval and surgeon satisfaction
This trial will test whether the HydroMARK Plus breast biopsy marker is retrieved more successfully than the current HydroMARK and whether surgeons are more satisfied with its removal for patients having biopsy clips removed during surgery.
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Valemetostat with atezolizumab and bevacizumab for advanced hepatocellular carcinoma
This will test whether adding the oral drug valemetostat to atezolizumab and bevacizumab helps people with advanced hepatocellular carcinoma who have not received prior systemic therapy.
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Investigating brain imaging in early Parkinson's Disease
This study is testing a brain imaging tool to see how it works in people with early Parkinson's Disease compared to healthy volunteers over two years.
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Preventing Acute GVHD After Stem Cell Transplant
This study is testing a new way to give a medication before and during stem cell transplants to see if it can help prevent a serious condition called acute GVHD in patients.
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Evaluating Pirfenidone for Recurrent Acute Pancreatitis
This study is testing if the drug pirfenidone can help people with recurrent acute pancreatitis feel better and prevent future attacks.
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Impact of a DASH diet on kidney stone risk factors
This study tests if following a DASH-style diet can lower the risk of kidney stones in people who have already had them.
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Improving physical activity for people with mobility impairments
This study is testing whether providing exercise videos and health coaching can help people with mobility challenges become more active and stay motivated over 32 weeks.
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Early selumetinib to try to prevent plexiform neurofibromas in young children with NF1
This trial will see if giving selumetinib to young children with NF1 who are at high risk can prevent or slow the development of plexiform neurofibromas.
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Improving decision-making for chronic kidney disease patients and their caregivers
This study is testing a program to help patients with stage 4 chronic kidney disease and their caregivers make better health decisions together.
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Using brain stimulation to improve treatment for Parkinson's disease
This study is testing how different types of brain stimulation can improve treatment for people with Parkinson's disease by looking at how it affects their brain activity and movement over time.
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Using expressive writing to help adults with spinal cord injuries cope with grief
This study is testing whether a 10-week online writing program can help adults with spinal cord injuries cope with their grief and improve their emotional well-being.
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Comparing carbon dioxide and air for endoscopy in children
This study is testing whether using carbon dioxide instead of air during endoscopy can make the procedure safer and more comfortable for children aged 6 months to 18 years.
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Low dose capecitabine for older patients with advanced breast cancer
This study is testing if a lower dose of capecitabine can help older patients with advanced breast cancer feel better after their previous treatments.
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Investigating how opioid use affects sleep and circadian rhythms
This study is trying to see how opioid use affects sleep and body clock patterns in people with opioid use disorder to find better ways to help them recover.
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Infusion of selected stem cells to improve graft function in blood cancer patients
This study is testing if infusing special stem cells can help blood cancer patients who have had problems with their stem cell transplant feel better and avoid complications.
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High-intensity exercise to improve cognitive function in older adults with HIV
This study tests whether high-intensity exercise can help older adults with HIV think better and stick to their workout routines compared to regular moderate exercise.
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Therapy to improve control and reduce symptoms in children with non-epileptic seizures
This study is testing a new therapy called ReACT to see if it can help children aged 11-18 with non-epileptic seizures feel more in control and reduce their symptoms.
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Pilot project on treating hypertension during pregnancy
This study is testing if treating high blood pressure earlier in pregnant women can help improve their baby's birth weight compared to usual care.
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High-intensity exercise program for older adults with HIV to improve vascular and cognitive health
This study tests whether a 16-week high-intensity exercise program can help older adults with HIV improve their heart and brain health compared to a moderate exercise routine.
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Neoadjuvant chemotherapy for newly diagnosed advanced ovarian cancer
This study is testing a new combination of chemotherapy drugs for people with newly diagnosed advanced ovarian cancer to see if it helps them before surgery.
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Investigating brain activity during cognitive tasks
This study is testing how brain activity changes during thinking and memory tasks in people who need surgery, to help find better treatments for cognitive issues like dementia and attention disorders.
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Follow-up on health outcomes in patients with histiocytic disorders
This study looks at the long-term health effects of histiocytic disorders on around 6000 patients to see how these conditions impact their overall well-being and quality of life.
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Understanding recovery patterns in sepsis patients after ICU care
This study looks at how people who survived sepsis and spent time in the ICU recover over time, especially to see how hospital readmissions affect their physical strength and function.
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Training program to improve end-of-life care for older African Americans
This study is testing a training program for healthcare providers to improve end-of-life care for older African Americans by focusing on their cultural values and experiences.
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Understanding treatment outcomes in lymphoma-related hemophagocytic lymphohistiocytosis
This study looks at how people with lymphoma who develop a serious condition called hemophagocytic lymphohistiocytosis are treated and what the outcomes are, to find better ways to help them survive.
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Using a smartphone brain-training app to reduce chemo‑brain in gynecologic cancer patients
This will test whether a mobile cognitive training app can reduce chemo‑brain symptoms in people with gynecologic cancers who are receiving chemotherapy.
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Understanding brain emotion processing in epilepsy patients
This study is trying to understand how people with epilepsy process emotions in their brains to see if new treatments can help improve their emotional health.
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Feasibility of a new mind and body treatment for pediatric functional seizures
This study is testing if two different treatments for kids with functional seizures work well enough to be used in a larger trial.
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Exploring how sex, hormones, and identity affect pain sensitivity
This study is trying to see how gender identity and hormone levels affect how different people feel pain.
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Diet changes for managing knee pain based on race
This study is testing if a low-carbohydrate diet can help reduce knee pain in adults with osteoarthritis, focusing on differences between Black and White participants.
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Combining a ketogenic diet with cognitive training for blood cancer survivors
This study is testing if a special diet combined with online brain training can help blood cancer survivors think better over 12 weeks.
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Lowering blood pressure in pregnant women with hypertensive disorders to prolong pregnancy
This study is testing if lowering blood pressure in pregnant women with high blood pressure can help them stay pregnant longer and improve outcomes for both mom and baby.
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Examining the gut microbiome's effects on metabolic and bowel function after spinal cord injury
This study is trying to see how the gut bacteria of people with a recent spinal cord injury affects their metabolism and bowel function over the first year after the injury.
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Virtual magic trick training for adolescents with autism
This study is testing whether a virtual magic trick training program can help teenagers with autism improve their social skills and reduce stress.
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Imaging neuroinflammation in patients with neurological issues after COVID-19 infection
This study is testing a special imaging method to see if there is inflammation in the brains of people who have long-term symptoms after COVID-19, compared to healthy volunteers.
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Prehabilitation program for older adults undergoing stem cell transplantation
This study is testing if an 8-week home exercise program can help older adults with Multiple Myeloma feel stronger before and after their stem cell transplant compared to just getting nutrition advice.
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New imaging approach for assessing high grade glioma after radiation therapy
This study is testing a new imaging method to see if it can help doctors find active high grade glioma in kids and adults after they've had radiation therapy.
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Exploring how social reward learning affects social pleasure in first-episode psychosis
This study is testing whether different types of support can help young adults who have just experienced their first episode of psychosis feel more pleasure from social interactions.
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Movement-to-Music exercise program for wheelchair users with cardiometabolic risks
This study is testing a 24-week exercise program that uses music to see if it can help wheelchair users improve their heart and metabolic health better than regular exercise videos.
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Combining Cabozantinib and Dostarlimab for Recurrent Gynecologic Carcinosarcoma
This study is testing if combining two drugs, Cabozantinib and Dostarlimab, can help people with recurrent gynecologic carcinosarcoma who have already had chemotherapy.
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Registry for older adults with blood cancers
This study is creating a registry for older adults with blood cancers to see how their health changes over time and to support future research.
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Epidural spinal cord stimulation for managing blood pressure and low back pain
This study is testing if epidural spinal cord stimulation can help people with chronic low back pain and high blood pressure feel better by lowering their blood pressure and relieving their pain.
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Improving arm use after stroke with therapy and sensory techniques
This study is testing if adding sensory techniques to a therapy for stroke patients can help them use their affected arm better after treatment.
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Examining inflammatory genes in patients with hidradenitis suppurativa
This study is trying to see if certain inflammatory genes are different in people with hidradenitis suppurativa compared to healthy individuals, and it also looks at how childhood trauma might affect this skin condition.
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Therapy to improve arm use in adults after mild stroke
This study is testing a special therapy to help adults who had a mild stroke use their affected arm better in daily activities.
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Comparing two types of grafts for ACL reconstruction
This study is testing which type of graft, quadriceps tendon or bone-patellar tendon-bone, helps people recover better after ACL surgery.
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Understanding visual learning and plasticity in macular degeneration
This study is testing if training can help people with macular degeneration improve their everyday vision by understanding how their brains adapt to changes in sight.
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Identifying biomarkers for depression and suicide in adolescents
This study is trying to find specific markers in the body that can help understand depression and suicidal thoughts in teenagers, while also looking at how standard treatments affect these issues.
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Understanding how dietary oxalate affects kidney stones and immunity
This study tests how different amounts of oxalate in food affect kidney stones and the immune system in both healthy people and those with kidney stones.
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Evaluating a new approach to improve HIV testing and treatment in Alabama
This study is testing a new way to improve HIV testing and treatment in Mobile County, Alabama, by bringing testing to the community and helping people get care quickly.
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Using a new dental gel to improve gum health after cleaning
This study is testing if a new dental gel can help people with gum disease get even better results after their teeth cleaning treatment.
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Early-life exposures and breastfeeding in children with sickle cell disease
This project will try a community breastfeeding support group for mothers of infants with sickle cell disease to see if breastfeeding and related supports improve early-life exposures and child health.
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Telehealth intervention to help adolescents with sickle cell disease transition to adult care
This study is testing a telehealth program to help teenagers with sickle cell disease improve their thinking skills and self-care as they transition to adult healthcare.
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Understanding how the brain processes language
This study tests how the brains of people with epilepsy understand language by recording their brain activity while they read or listen to sentences.
Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.
NIH-funded research (newest 40 of 1232)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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IOP and CSF Pressure in Glaucoma Risk
This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.
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Exploring how Down syndrome affects optic nerve health in kids
A study using a mouse model to understand why optic nerve problems are common in children with Down syndrome and how to prevent them.
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Global bromocriptine trial for postpartum cardiomyopathy
A large international study will test whether adding bromocriptine to standard heart failure treatment helps new mothers with peripartum cardiomyopathy.
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Global Bromocriptine Add-on for Postpartum Heart Failure (GLOBal PPCM)
A large international study will test whether adding the dopamine agonist bromocriptine to standard heart failure care helps postpartum women with a specific heart condition.
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Global Bromocriptine Trial for Postpartum Heart Failure (GLOBal PPCM)
A large international study will test whether adding bromocriptine to standard heart-failure care helps women with postpartum cardiomyopathy.
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Bromocriptine as add-on therapy for postpartum cardiomyopathy across multiple sites
A large international study will test whether adding bromocriptine to standard heart failure treatment helps new mothers with postpartum cardiomyopathy.
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Global bromocriptine trial to help postpartum heart failure patients
A large international trial tests whether adding bromocriptine to standard heart failure treatment improves outcomes for new mothers with a specific pregnancy-related heart condition.
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Global Bromocriptine Trial to Help Postpartum Heart Failure
A large international study will test whether adding bromocriptine to standard heart failure treatment helps women with postpartum cardiomyopathy.
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Bromocriptine Added to Standard Care for Postpartum Heart Muscle Disease (GLOBal PPCM)
A large international study will test whether adding the drug bromocriptine to standard heart failure treatment helps women with postpartum cardiomyopathy.
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Global bromocriptine trial for postpartum heart muscle disease
A large international study will test whether adding bromocriptine to standard heart-failure treatment helps women with peripartum cardiomyopathy after delivery.
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Global bromocriptine trial for postpartum heart failure (PPCM)
A large international trial will test whether adding bromocriptine to standard heart failure treatment helps women with peripartum cardiomyopathy after giving birth.
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Bromocriptine addition for postpartum cardiomyopathy in a global trial
A large international study will test whether adding bromocriptine to standard heart failure therapy helps women after childbirth who have PPCM.
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Global Bromocriptine Trial for Postpartum Heart Disease (PPCM)
A large international trial will test whether adding bromocriptine to standard heart-failure treatment improves outcomes for women with postpartum cardiomyopathy.
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Global Bromocriptine Trial for Postpartum Heart Failure (GLOBal PPCM)
This study tests whether adding bromocriptine to standard heart failure treatment helps women with peripartum cardiomyopathy after giving birth.
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Bromocriptine added to standard therapy for postpartum heart failure (Global PPCM)
A large, multi-country trial will test whether adding bromocriptine to usual heart failure treatment improves outcomes for women with postpartum cardiomyopathy.
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Primary Care HEART-NET: boosting access to research in the Deep South
A collaboration across three universities will build primary care research networks in Alabama, Arkansas, and Mississippi to improve access to care and help prevent and manage chronic diseases.
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UMPIRE Protocol: Improving Kidney Health for Children with Spina Bifida
A long-term plan to standardize how doctors care for babies and young kids with spina bifida to protect their kidney function.
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Improving care and outcomes for people with Spina Bifida through a national registry
A long-term project uses a national health registry to understand and improve care for people with spina bifida.
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Targeted progranulin therapy for TDP-43 proteinopathy
A potential new therapy aims to raise progranulin levels to help people affected by TDP-43 proteinopathy, a driver of ALS, some forms of FTD, and Alzheimer’s-related changes.
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Understanding how heparan sulfate affects alpha-synuclein in Lewy body dementia
A small study in people who have dementia with Lewy bodies looks at how a brain sugar (heparan sulfate) helps a harmful protein (alpha-synuclein) spread, with the hope of slowing disease progression.
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UAB HIV Implementation Science Hub: Building Real-World Ways to End the HIV Epidemic
A regional hub in the Deep South is helping researchers and communities implement proven HIV strategies to reduce new infections and improve care.
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HBV-specific T cells in HBV/HIV coinfection
Researchers are studying how liver-targeted immune cells respond in people living with both HIV and hepatitis B to guide better therapies.
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How choosing PrEP products could improve HIV protection for young women in Kenya
This project looks at which HIV-prevention options young Kenyan women prefer and how choosing a product affects how well they stay protected.
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Effectiveness of PrEP product choice for HIV prevention among young Kenyan women seeking reproductive health services
A study tests which PrEP options best help young Kenyan women stay protected against HIV when they access reproductive health services.
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All of Us Southern Network expansion supports diverse pediatric participation
A nationwide research program is expanding its southern pediatric outreach to enroll more children under 21 to better understand health and COVID-19 impacts through diverse communities.
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Syphilis in Pregnancy: Understanding Infection in Moms and Babies
A study following pregnant women with syphilis and their babies to learn how the infection affects pregnancy and newborn health.
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Syphilis in Pregnancy: Molecular Tests and Immune Responses in Mom and Baby
A study to understand how syphilis affects pregnancy and newborns by using molecular tests and tracking immune responses in 750 pregnant women with syphilis and their babies.
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Cancer disparities research partnership improves care in underserved communities
A multi-institution collaboration in Alabama aimed at advancing cancer research and support for underserved populations through training, community engagement, and shared resources.
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Recombinant hemopexin for treating lung injury
A new plant-produced hemopexin therapy is being tested to help reduce acute and chronic lung injury after dangerous gas exposure in animal studies.
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Advanced HIV Disease: Re-Engagement in Care (ARC)
A clinical trial in Zambia tests a new support program to help people with advanced HIV disease stay engaged in care after hospital discharge.
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Molecular mechanisms to rebuild myelin in brain diseases
This grant looks at how to restore the protective myelin coating in diseases like Alzheimer’s and autism where nerve signals can be disrupted.
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Glial origins and signaling in childhood brain cancer (medulloblastoma)
A new study looks at how glial cells may drive relapse and growth in childhood medulloblastoma, with the goal of finding targeted treatments.
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Tobacco quit program for women using an online app
A women-focused, phone-based cessation program uses a mobile app to help low-income, rural, and working women quit smoking.
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Retinal biomarkers to detect early Alzheimer's disease
A study tests two new eye-based markers to identify Alzheimer’s early, using non-invasive eye imaging in older adults.
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Peer-led PrEP delivery for youth in Brazil: a community-based randomized trial
A youth-focused, community-based program tests whether trained young peers can help more adolescents get HIV PrEP in Brazil.
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Peer-led PrEP delivery for youth in Brazil: a youth-focused PrEP access trial
This project tests whether trained youth peer workers can deliver PrEP in community settings to increase PrEP uptake among young people in Brazil.
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Precision nutrition to tailor diets for people with chronic disease
A large study at UAB aims to personalize dietary recommendations for people with chronic disease using advanced data analysis.
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Misoprostol to Improve Cervical Cancer Screening in Africa
A study tests whether a cheap, single-dose misoprostol helps more women in Africa see the cervix clearly during screening, potentially catching precancerous changes earlier.
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Using everyday wearable tech to monitor kids in rural hospitals
A hospital-based program in Ghana will test if inexpensive consumer wearables can safely monitor children remotely to spot problems early.
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Protein-based MRI contrast agent to image lung fibrosis in kids and adults
A new protein MRI contrast agent is being developed to help doctors noninvasively detect and measure lung fibrosis, including in children and other patients, using safer MRI imaging.
Quick answers
How many clinical trials run by University of Alabama at Birmingham are recruiting right now?
200, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 16 countries. The most sites are in United States (190 trials), Zambia (4 trials), Brazil (2 trials), Kenya (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 18, Early Phase 1: 11, Phase 1: 10, Phase 4: 8. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.