Investigating brain activity during cognitive tasks

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore brain activity associated with cognitive tasks such as thinking, reasoning, and remembering to enhance understanding of cognitive impairments like dementia and attention deficit disorders. Participants, who are surgical candidates for intracranial monitoring, will have electrodes placed in their brains to record neural activity while performing various cognitive tasks. The study will also utilize additional sensors to monitor movements and other physiological responses without impacting clinical care. The goal is to identify changes in brain activity that could inform better treatment strategies for cognitive impairments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Eligible for surgery based on multi-disciplinary consensus review
* Have a diagnosis of medically-refractory epilepsy
* A minimum of 18 years of age
* Willingness to participate in the paradigms described in the protocol

Exclusion Criteria:

* Inability to provide full and informed consent
* Age younger than 18
* Are not physically able to participate in study-related activities
* Major medical or surgical complication

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting

Study contacts

• Principal investigator: Jessica N Bentley, MD — The University of Alabama at Birmingham
• Study coordinator: Jessica N Bentley, MD
• Email: jbentley@uabmc.edu
• Phone: 2059347170

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.