Understanding recovery patterns in sepsis patients after ICU care

Prediction of Sepsis Recovery Physical Performance Subtypes: A Pilot Study

Observational University of Alabama at Birmingham · NCT05912413

This study looks at how people who survived sepsis and spent time in the ICU recover over time, especially to see how hospital readmissions affect their physical strength and function.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorUniversity of Alabama at Birmingham Academic / other
Locations1 site (Birmingham, Alabama)
Trial IDNCT05912413 on ClinicalTrials.gov

What this trial studies

This observational study focuses on critically ill patients recovering from sepsis, particularly those who have required ICU care. It aims to capture and interpret various tests during the recovery trajectory of these patients, especially concerning the impact of hospital readmissions on their physical function. The study seeks to identify different recovery patterns among sepsis survivors, as many experience ongoing weakness and dysfunction after discharge. By closely tracking these recovery trajectories, the research intends to inform future rehabilitation interventions tailored to individual patient needs.

Who should consider this trial

Good fit: Ideal candidates for this study are patients who have experienced sepsis requiring organ support in an ICU setting.

Not a fit: Patients who are transitioning to palliative care or have significant comorbidities, such as recent cancer therapy or advanced age, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies for sepsis survivors, enhancing their recovery and reducing hospital readmissions.

How similar studies have performed: While there is ongoing research in the area of sepsis recovery, this study's specific focus on predicting recovery trajectories is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Sepsis requiring organ support in an ICU setting

Exclusion Criteria:

1. inability to obtain informed consent
2. the attending physician reports that the patient's goals of care are transitioning to palliation/withdrawal of life-sustaining therapy
3. recent cancer therapy in the last 12 months
4. age \>80
5. plans to be discharged on mechanical ventilation to a Long Term Acute Care Hospital
6. planned discharge to rehabilitation facility, long-term hospital or nursing home.
7. Pregnancy

Where this trial is running

Birmingham, Alabama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sepsis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.