Understanding recovery patterns in sepsis patients after ICU care
Official title: Prediction of Sepsis Recovery Physical Performance Subtypes: A Pilot Study
Run by University of Alabama at Birmingham · NCT05912413 · Data updated 2026-11-12
This study looks at how people who survived sepsis and spent time in the ICU recover over time, especially to see how hospital readmissions affect their physical strength and function.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | July 11, 2023 |
| Main results expected | December 15, 2027 |
| Study ends | December 15, 2027 |
| Registry record updated | February 19, 2026 |
| Trial ID | NCT05912413 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients who have experienced sepsis requiring organ support in an ICU setting.
✕Probably not a fit
Patients who are transitioning to palliative care or have significant comorbidities, such as recent cancer therapy or advanced age, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on critically ill patients recovering from sepsis, particularly those who have required ICU care. It aims to capture and interpret various tests during the recovery trajectory of these patients, especially concerning the impact of hospital readmissions on their physical function. The study seeks to identify different recovery patterns among sepsis survivors, as many experience ongoing weakness and dysfunction after discharge. By closely tracking these recovery trajectories, the research intends to inform future rehabilitation interventions tailored to individual patient needs.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation strategies for sepsis survivors, enhancing their recovery and reducing hospital readmissions.
How similar studies have gone: While there is ongoing research in the area of sepsis recovery, this study's specific focus on predicting recovery trajectories is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Sepsis requiring organ support in an ICU setting Exclusion Criteria: 1. inability to obtain informed consent 2. the attending physician reports that the patient's goals of care are transitioning to palliation/withdrawal of life-sustaining therapy 3. recent cancer therapy in the last 12 months 4. age \>80 5. plans to be discharged on mechanical ventilation to a Long Term Acute Care Hospital 6. planned discharge to rehabilitation facility, long-term hospital or nursing home. 7. Pregnancy
Where it's running
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University of Alabama at Birmingham (UAB) Hospital
Birmingham, Alabama, United States Recruiting
Study contacts
- Principal investigator: peter morris, md — University of Alabama at Birmingham
- Study coordinator: peter morris, md
- Email: pmorris@uabmc.edu
- Phone: (205) 934-5555
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Thymalfasin added to standard care for adults with sepsis and immune dysfunction
This study tests whether thymosin alpha-1 helps restore immune function in adults with sepsis who have weakened immunity.
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Multicenter group study of sepsis and ARDS in China
This study tests how sepsis and ARDS differ among adults across several Chinese hospitals and builds a biobank to understand why some patients do better or worse.
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Non-invasive hemodynamic guidance for sepsis care on medical wards
This trial tests whether guiding fluid and vasopressor therapy for sepsis using non-invasive hemodynamic measurements works better than standard care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.