Folic Acid–Fortified Salt for Women of Reproductive Age in Zambia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This nonrandomized intervention gives participants salt fortified with folic acid to replace their regular salt for six months. Researchers measure serum and red blood cell folate four times and collect survey data to evaluate acceptability. The study aims to see if FISFA increases folate levels and could reduce folate-related neural tube defect risk, while also monitoring taste and color acceptability. Participants must meet age and pregnancy status criteria and agree not to share study salt. The trial is conducted through collaboration between the University of Alabama at Birmingham and Zambian partners.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Voluntary participation in the study
* Do not intend to get pregnant
* Not lactating or pregnant
* Live alone or with a partner if they can be compliant and not share the study salt.
* Aged between 18 and 45 years

Exclusion Criteria:

* Pregnant or lactating

Where it's running

• Centre for Infectious Disease Research in Zambia
  Lusaka, Zambia Recruiting
• University of Alabama at Birmingham
  Birmingham, Alabama, United States Active not recruiting

Study contacts

• Principal investigator: Anastasia A Smith, DrPH — University of Alabama at Birmingham
• Study coordinator: Anastasia A Smith, DrPH
• Email: anastasia.arynchyna@childrensal.org
• Phone: 205-276-1067

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Fetoscopic repair of neural tube defects

  This study looks at how well a special surgery done before birth can help babies with spina bifida and what happens to them after the procedure.

  Recruiting Oregon Health and Science University · Portland, Oregon · NCT06946563

• Evaluating devices for repairing neural tube defects in fetoscopic procedures

  This study is testing new tools to see if they make it safer and easier to fix neural tube defects in unborn babies during a special type of surgery.

  Recruiting Baylor College of Medicine · Houston, Texas · NCT05672849

• Comparing two surgical methods for correcting fetal myelomeningocele

  This study is testing two different surgical methods to see which one works better and is safer for fixing a serious birth defect called fetal myelomeningocele before the baby is born.

  Recruiting at 2 sites USFetus · Los Angeles, California and 1 other locations · NCT03856034

• Evaluating patterns in neurodevelopmental disorders

  This study is trying to find common signs and causes of neurodevelopmental disorders like Autism and Down Syndrome to help with earlier diagnosis and better outcomes for those affected.

  Recruiting Rossignol Medical Center · Phoenix, Arizona · NCT06213090

• First-Trimester Screening for Open Neural Tube Defects with Fetal Biometrics and Maternal Markers

  This study tests whether early ultrasound measures and maternal blood markers can help screen for open neural tube defects in the first trimester.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07864142

• FRα expression in high-grade serous ovarian cancer (FRα positive)

  A retrospective study in Greece will test how often Folate Receptor Alpha is present in tumor samples from adults diagnosed with high-grade serous ovarian cancer.

  Recruiting Hellenic Cooperative Oncology Group · Athens · NCT07889843

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.