Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Therapy to improve arm use in adults after mild stroke

Official title: Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment and Deficits in Desired Occupational Performance: A Pilot Study

Run by University of Alabama at Birmingham · NCT05492513 · Data updated 2026-11-12

This study is testing a special therapy to help adults who had a mild stroke use their affected arm better in daily activities.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment12 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedDecember 8, 2022
Main results expectedNovember 2026
Study endsMarch 2027
Registry record updatedFebruary 20, 2026
Trial IDNCT05492513 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults who are at least six months post-stroke and demonstrate specific minimum active movement criteria in their affected upper extremity.

Probably not a fit

Patients who have severe cognitive impairments or cannot provide informed consent may not benefit from this therapy.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates Constraint-Induced Movement Therapy (CI Therapy) aimed at adults who have experienced a mild stroke and have upper extremity impairment. The therapy involves intensive daily sessions that include motor training, behavioral strategies, and reminders to use the affected arm in daily activities. Participants will engage in structured exercises designed to enhance the use and function of their more-affected upper extremity, with the goal of improving their ability to perform complex tasks in everyday life. The effectiveness of this approach will be measured using the Motor Activity Log to assess improvements in both the amount and quality of arm use.

Why it matters

Potential benefit: If successful, this therapy could significantly enhance the functional independence and quality of life for stroke survivors with mild upper extremity impairments.

How similar studies have gone: Previous studies on CI therapy have shown promising results in improving upper extremity function in stroke patients, indicating that this approach is supported by existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 6 months post stroke
* The ability to demonstrate the minimum UE active movement criteria of 20 degrees of wrist extension from a fully flexed position, 10 degrees of thumb extension or abduction, and 10 degrees of extension of all finger joints.
* Mean score of \>2.5 on the Motor Activity Log indicating the participant's use of the more-affected UE.

Exclusion Criteria:

* Score\< 24 on the Mini Mental State Exam
* Inability to answer the MAL questions and/or provide informed consent
* The inability to come in to the laboratory setting for treatment.

Where it's running

  • University of Alabama at Birmingham
    Birmingham, Alabama, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.