Therapy to improve arm use in adults after mild stroke
Official title: Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment and Deficits in Desired Occupational Performance: A Pilot Study
Run by University of Alabama at Birmingham · NCT05492513 · Data updated 2026-11-12
This study is testing a special therapy to help adults who had a mild stroke use their affected arm better in daily activities.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 12 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | December 8, 2022 |
| Main results expected | November 2026 |
| Study ends | March 2027 |
| Registry record updated | February 20, 2026 |
| Trial ID | NCT05492513 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults who are at least six months post-stroke and demonstrate specific minimum active movement criteria in their affected upper extremity.
✕Probably not a fit
Patients who have severe cognitive impairments or cannot provide informed consent may not benefit from this therapy.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates Constraint-Induced Movement Therapy (CI Therapy) aimed at adults who have experienced a mild stroke and have upper extremity impairment. The therapy involves intensive daily sessions that include motor training, behavioral strategies, and reminders to use the affected arm in daily activities. Participants will engage in structured exercises designed to enhance the use and function of their more-affected upper extremity, with the goal of improving their ability to perform complex tasks in everyday life. The effectiveness of this approach will be measured using the Motor Activity Log to assess improvements in both the amount and quality of arm use.
Why it matters
Potential benefit: If successful, this therapy could significantly enhance the functional independence and quality of life for stroke survivors with mild upper extremity impairments.
How similar studies have gone: Previous studies on CI therapy have shown promising results in improving upper extremity function in stroke patients, indicating that this approach is supported by existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least 6 months post stroke * The ability to demonstrate the minimum UE active movement criteria of 20 degrees of wrist extension from a fully flexed position, 10 degrees of thumb extension or abduction, and 10 degrees of extension of all finger joints. * Mean score of \>2.5 on the Motor Activity Log indicating the participant's use of the more-affected UE. Exclusion Criteria: * Score\< 24 on the Mini Mental State Exam * Inability to answer the MAL questions and/or provide informed consent * The inability to come in to the laboratory setting for treatment.
Where it's running
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University of Alabama at Birmingham
Birmingham, Alabama, United States Recruiting
Study contacts
- Study coordinator: Mary H Bowman, BS OT
- Email: mbowman@uab.edu
- Phone: 2059340069
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.