Prehabilitation program for older adults undergoing stem cell transplantation
Feasibility of a Prehabilitation Intervention Among Older Adults With Myeloma Receiving Autologous Stem Cell Transplant
This study is testing if an 8-week home exercise program can help older adults with Multiple Myeloma feel stronger before and after their stem cell transplant compared to just getting nutrition advice.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Trial ID | NCT05642884 on ClinicalTrials.gov |
What this trial studies
This pilot trial investigates the feasibility of a prehabilitation program for older adults aged 60 and above who are scheduled for Autologous Stem Cell Transplantation due to Multiple Myeloma. Participants will be randomly assigned to either an 8-week home-based exercise program delivered via telehealth or an attention control group receiving nutrition counseling. The study aims to assess the feasibility and acceptability of the prehabilitation program, as well as its impact on physical function at the time of transplant and 12 weeks post-transplant. Assessments will be conducted at baseline, during the transplant, and at follow-up to evaluate outcomes.
Who should consider this trial
Good fit: Ideal candidates are older adults aged 60 and above diagnosed with Multiple Myeloma and scheduled for Autologous Stem Cell Transplantation at UAB.
Not a fit: Patients at high risk for impending pathologic fracture may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could enhance physical function and overall recovery for older adults undergoing stem cell transplantation.
How similar studies have performed: While similar prehabilitation approaches have shown promise in other populations, this specific application in older adults undergoing stem cell transplantation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of Multiple Myeloma * Scheduled for ASCT at UAB within 10 weeks of study enrollment * age at ASCT ≥60y Exclusion Criteria: * at high risk for impending pathologic fracture using Mirels score
Where this trial is running
Birmingham, Alabama
- Kirklin Clinic of UAB Hospital — Birmingham, Alabama, United States (Recruiting)
Study contacts
- Study coordinator: Landon Martin, BS
- Email: landoncmartin@uabmc.edu
- Phone: 205-638-2120
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.