Clinical trial Recruiting at 1 site Interventional Ages 60 and up

Prehabilitation program for older adults undergoing stem cell transplantation

Official title: Feasibility of a Prehabilitation Intervention Among Older Adults With Myeloma Receiving Autologous Stem Cell Transplant

Run by University of Alabama at Birmingham · NCT05642884 · Data updated 2026-11-12

This study is testing if an 8-week home exercise program can help older adults with Multiple Myeloma feel stronger before and after their stem cell transplant compared to just getting nutrition advice.

Quick facts

Study typeInterventional
Ages60 Years and up
SexAll
Enrollment30 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedJuly 10, 2023
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedDecember 24, 2025
Trial IDNCT05642884 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are older adults aged 60 and above diagnosed with Multiple Myeloma and scheduled for Autologous Stem Cell Transplantation at UAB.

Probably not a fit

Patients at high risk for impending pathologic fracture may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot trial investigates the feasibility of a prehabilitation program for older adults aged 60 and above who are scheduled for Autologous Stem Cell Transplantation due to Multiple Myeloma. Participants will be randomly assigned to either an 8-week home-based exercise program delivered via telehealth or an attention control group receiving nutrition counseling. The study aims to assess the feasibility and acceptability of the prehabilitation program, as well as its impact on physical function at the time of transplant and 12 weeks post-transplant. Assessments will be conducted at baseline, during the transplant, and at follow-up to evaluate outcomes.

Why it matters

Potential benefit: If successful, this program could enhance physical function and overall recovery for older adults undergoing stem cell transplantation.

How similar studies have gone: While similar prehabilitation approaches have shown promise in other populations, this specific application in older adults undergoing stem cell transplantation is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of Multiple Myeloma
* Scheduled for ASCT at UAB within 10 weeks of study enrollment
* age at ASCT ≥60y

Exclusion Criteria:

* at high risk for impending pathologic fracture using Mirels score

Where it's running

  • Kirklin Clinic of UAB Hospital
    Birmingham, Alabama, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.