Tinted daily contact lenses for light sensitivity after a concussion

Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity

Not applicable Interventional University of Alabama at Birmingham · NCT07223086

This project will try daily disposable tinted contact lenses to reduce light sensitivity in adults who have had a mild concussion.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Alabama at Birmingham Academic / other
Locations1 site (Birmingham, Alabama)
Trial IDNCT07223086 on ClinicalTrials.gov

What this trial studies

This pilot interventional study at the University of Alabama at Birmingham will compare narrow-band tinted daily disposable contact lenses with clear daily disposable contact lenses in adults who experienced a mild traumatic brain injury. Eligible participants are adults within 24 months of their concussion who report photophobia or changes in light sensitivity and who can safely insert and remove contacts. Participants will wear the assigned lenses and researchers will collect symptom measures of photophobia and functional outcomes such as return-to-work or school. The goal is to gather preliminary data on whether tinted lenses decrease light sensitivity after concussion and support larger trials.

Who should consider this trial

Good fit: Adults aged 18 or older with a diagnosed mild traumatic brain injury within the past 24 months who have increased light sensitivity and can safely use daily disposable contact lenses are ideal candidates.

Not a fit: Patients with moderate or severe traumatic brain injury, active eye infection or inflammation, or those unable to safely insert and remove contact lenses are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, tinted daily contact lenses could reduce light sensitivity and help adults with mild concussion return to work or school more comfortably.

How similar studies have performed: Small prior studies and clinical reports suggest tinted lenses or colored filters can reduce photophobia in migraine and concussion, but robust randomized evidence is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosed mild traumatic brain injury (concussion)
* age 18 or older
* Within 24 months of initial injury
* experiencing symptoms of photophobia (light sensitivity), increased photophobia since the injury, or no symptoms of photophobia

Exclusion Criteria:

* moderate or severe concussion
* active infection or inflammation that contradicts the use of soft contact lenses
* subjects unable to safely perform insertion and removal of the contact lenses

Where this trial is running

Birmingham, Alabama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Concussion, MildPhotophobiaContact LensMild concussiontinted contact lenseslight sensitivity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.