Peer-led PrEP delivery for youth in Brazil: a community-based randomized trial
Official title: Determining the impact of peer-led, community-based PrEP delivery among youth in Brazil: A randomized controlled trial
Funded at University of Alabama at Birmingham · NIH-11528283 · Data updated 2026-11-12
A youth-focused, community-based program tests whether trained young peers can help more adolescents get HIV PrEP in Brazil.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | July 19, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $248,765 |
| NIH project number | 3R01MH135769-03S2 |
| Project ID | NIH-11528283 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are HIV-negative youth in Brazil and similar settings who are at risk and open to receiving PrEP through peer-led, community-based services.
✕Less likely to help
Youth who are not considering PrEP or who prefer traditional clinic-based services may see little personal benefit.
What this research studies
This project tests a model where trained youth peers work with healthcare teams to bring PrEP to communities instead of relying only on clinics. It uses a randomized design to compare PrEP uptake and engagement between peer-led delivery in community venues and standard care. The approach is designed to reduce stigma and logistical barriers that youth face when accessing PrEP. The study builds on prior research from PrEP1519 and aims to refine and scale up effective, youth-friendly PrEP delivery.
Why it matters
Potential benefit: If successful, more HIV-negative teens and young adults could start or continue PrEP, potentially reducing new infections.
How similar studies have gone: Previous adolescent-focused PrEP work showed that peer-delivered approaches can be acceptable and feasible, but broader uptake requires community-based options.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Bruxvoort, Katia — University of Alabama at Birmingham
- Study coordinator: Bruxvoort, Katia
Related research
Other NIH-funded projects on the same topics.
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A brief alcohol support for PrEP users to boost HIV prevention
A short, friendly program helps people starting or restarting PrEP in Vietnam drink less and stick with PrEP to stay protected.
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Peer-led PrEP delivery for youth in Brazil: a youth-focused PrEP access trial
This project tests whether trained youth peer workers can deliver PrEP in community settings to increase PrEP uptake among young people in Brazil.
-
Peer-led PrEP delivery for youth in Brazil: a trial to boost PrEP uptake
A youth-focused program tests whether trained young peers delivering PrEP in community settings can help more teens in Brazil start and stay on PrEP.
-
Brief alcohol help to improve PrEP use in Vietnam
A short, friendly program helps people starting or restarting PrEP in Vietnam to drink less and stick with PrEP to prevent HIV.
-
Helping people on PrEP reduce drinking and stay on HIV prevention
A short counseling program using motivational interviewing and CBT aims to help people on PrEP who drink at risky levels cut back and keep taking their HIV prevention medicine.
-
W-PrEP: clinic-level steps to help women get PrEP for HIV prevention
A clinic-level program helps healthcare teams better offer and support PrEP for women to prevent HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.