Clinical trial Recruiting at 1 site Interventional Ages 18 to 89

Improving arm use after stroke with therapy and sensory techniques

Official title: Constraint-Induced Movement Therapy Plus Sensory Components for Adults With Mild-to-Severe Arm and Hand Impairment After Stroke

Run by University of Alabama at Birmingham · NCT05515237 · Data updated 2026-11-12

This study is testing if adding sensory techniques to a therapy for stroke patients can help them use their affected arm better after treatment.

Quick facts

Study typeInterventional
Ages18 Years to 89 Years
SexAll
Enrollment15 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedMarch 30, 2023
Main results expectedMarch 2027
Study endsJune 2027
Registry record updatedApril 13, 2026
Trial IDNCT05515237 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals who are at least six months post-stroke and can demonstrate minimal active movement in their affected upper extremity.

Probably not a fit

Patients with severe cognitive impairments or those unable to participate in the therapy due to physical limitations may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the feasibility of enhancing Constraint-Induced Movement Therapy (CI Therapy) by incorporating sensory components for stroke patients with varying levels of upper extremity impairment. The intervention involves intensive treatment over two to three weeks, focusing on improving the use and motor ability of the more-affected arm through behavioral strategies and motor training techniques. Participants will be assessed using specific measures to evaluate their arm use and motor capacity before and after the intervention. The goal is to determine if adding sensory components can further improve recovery outcomes for stroke survivors.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the functional use of the affected arm in daily activities for stroke patients.

How similar studies have gone: Previous studies have shown strong evidence supporting the effectiveness of CI Therapy in improving upper extremity function after stroke, indicating that this approach may build on established methods.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 6 months post stroke
* The ability to demonstrate the minimum UE active movement criteria of shoulder ≥ 30 toward flexion or abduction, initiate movement at the elbow for flexion and extension, and initiate movement at the wrist, fingers, or thumb.
* Mean score of \<2.5 on the Motor Activity Log/ G4/5 Motor Activity Log indicating the participant's use of the more-affected UE.

Exclusion Criteria:

* Score\< 24 on the Mini Mental State Exam
* Inability to answer the MAL/ G4/5 MAL questions and/or provide informed consent
* The inability to come in to the laboratory setting for treatment.

Where it's running

  • University of Alabama at Birmingham
    Birmingham, Alabama, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.