Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Brief online activities to change mood and attitudes in people with psychotic disorders and healthy adults

Official title: Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy Controls

Run by University of Alabama at Birmingham · NCT06911723 · Data updated 2026-11-12

This project will try short online activities to see if they can improve mood and attitudes for adults with psychotic disorders and for healthy adults.

More Schizophrenia Disorders trials

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment200 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedAugust 20, 2025
Main results expectedOctober 2028
Study endsDecember 2028
Registry record updatedAugust 31, 2026
Trial IDNCT06911723 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are adults 18-65 with a diagnosed psychotic disorder or healthy adults without a current DSM-5 diagnosis who can complete brief online activities.

Probably not a fit

People with severe cognitive impairment, unstable psychiatric or medical conditions, or who cannot access or use online tasks may not receive benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study tests whether brief online activities are acceptable and can produce short-term changes in mood and attitudes. Adults aged 18-65 with a diagnosed psychotic disorder (schizophrenia group) and healthy controls without a current DSM-5 diagnosis will complete the activities and mood measures. The protocol uses brief, web-delivered tasks and compares responses between the clinical and healthy samples to look for initial signals of benefit. The work is focused on feasibility and preliminary efficacy and is conducted at the University of Alabama at Birmingham.

Why it matters

Potential benefit: If successful, these brief online activities could offer a low-cost, easy-to-access way to boost mood and attitudes for people with psychotic disorders.

How similar studies have gone: Related online activity-based interventions have shown mood benefits in depression, but this specific approach is relatively untested in schizophrenia-spectrum samples.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged 18-65
* schizophrenia group - have a psychotic disorder diagnosis
* healthy control group - Do not have a current DSM-5 diagnosis via the SCID-5

Where it's running

  • University of Alabama at Birmingham
    Birmingham, Alabama, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.