Early-life exposures and breastfeeding in children with sickle cell disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a small randomized pilot in which 20 mother–infant pairs will be assigned to a community-based breastfeeding support group or to observation. The team will track acceptability of enrollment, adherence to the intervention for at least six months, and preliminary signals of effectiveness. Researchers will collect data on adverse childhood experiences, social determinants of health, and biomarkers of inflammation, and will compare development of asthma and the frequency of pain episodes and acute chest syndrome between groups. The intervention also includes behavioral components aimed at strengthening maternal psychological resilience and supportive lifestyle practices.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* mother of infant with sickle cell disease
* resides within the city of Birmingham, Alabama or in close proximity

Exclusion Criteria:

* prescribed teratogenic medications
* no/limited internet access

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting

Study contacts

• Principal investigator: Brandi M Pernell, DNP, MSPH — University of Alabama at Birmingham
• Study coordinator: Brandi M Pernell, DNP, MSPH
• Email: brandimcclain@uabmc.edu
• Phone: 2058640238

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.