Epidemiology and care for dialysis in ICU patients with severe acute kidney injury in Latin America

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an international, multicenter observational registry enrolling adults with KDIGO stage 3 acute kidney injury who start renal replacement therapy around the time of ICU admission in Latin America. The study will capture standardized clinical, laboratory, treatment, process-of-care, and outcome data and pool them into a comprehensive database. Investigators will compare processes of care and outcomes between countries and analyze how demographic, clinical, and socioeconomic factors influence patient trajectories. The dataset is intended to support regional benchmarking and to be a resource for future clinical research and guideline development.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient (≥18) admitted to the ICU
* First ICU admission during current hospitalization
* Diagnosis of acute kidney injury stage 3 according to KDIGO guidelines
* RRT initiated no earlier than 3 days before or no later than 7 days after ICU admission

Exclusion Criteria:

* Transfer from outside hospital with ongoing RRT
* RRT exposure of less than 2 days (if CRRT or PD was provided) or less than 2 HD/SLED sessions
* Kidney failure (ESRD) patients on maintenance dialysis
* Kidney transplant recipients
* Previous or new diagnosis of glomerulonephritis

Where it's running

• Hospital Obrero No 2
  Cochabamba, Bolivia Recruiting
• Fundación Cardioinfantil
  Bogotá, Colombia Recruiting
• Hospital San Jose de Popayan
  Popayán, Colombia Recruiting
• Hospital General de la Plaza de la Salud
  Santo Domingo, Dominican Republic Recruiting
• Hospital Civil de Guadalajara
  Guadalajara, Mexico Recruiting
• Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
  Mexico City, Mexico Recruiting

Study contacts

• Principal investigator: Javier A Neyra, MD, MSCS — University of Alabama at Birmingham
• Study coordinator: Javier A Neyra, MD, MSCS
• Email: jneyra@uabmc.edu
• Phone: 205-975-2021

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.