Wearing special contact lenses to slow nearsightedness in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to determine if wearing specialized soft contact lenses can slow the progression of myopia in children. Participants will wear either one type of lens or alternate between two types of lenses daily for a year. The study will involve regular clinic visits for checkups and tests, as well as diary entries to track lens-wearing times. The research focuses on the effectiveness, compliance, and safety of these lenses in managing childhood myopia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Spherical component of refractive error in primary meridian between -0.75 and -5.00 D
* Less than 1.00 D of astigmatism or anisometropia
* History of soft contact lens wear for at least a week
* Best-corrected visual acuity of 20/25 (+0.10 logMAR) or better in each eye
* Willingness to wear the lenses for a minimum of 10 hours/day, at least six days a week for the duration of the study

Exclusion Criteria:

* Subjects receiving myopia control treatments within the past six months
* History of premature (less than 3.3 lb) or preterm birth (earlier than 30 weeks)
* Current history of using systemic or ocular medications (including artificial tears) that may affect contact lens wear, tear film health, refractive state, pupillary response or accommodative function
* History of ocular or systemic diseases, including those that may affect refractive development
* Known allergy to fluorescein, benoxinate, proparacaine, or tropicamide
* Contact lens contraindications (e.g., giant papillary keratoconjunctivitis)
* Corneal disorders (e.g., hypoesthesia, keratoconus)
* Strabismus at distance or near with distance glasses or contact lenses
* Subjects exhibiting poor personal hygiene that may affect the compliance of contact lens wear.

Where it's running

• University of Alabama at Birmingham School of Optometry
  Birmingham, Alabama, United States Recruiting

Study contacts

• Principal investigator: Safal Khanal, OD, PhD — Unversity of Alabama at Birmingham
• Study coordinator: Sindhu Gurrala, MPH
• Email: sgurral2@uab.edu
• Phone: 205.975.3881

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.