Advanced HIV Disease: Re-Engagement in Care (ARC)
Funded at University of Alabama at Birmingham · NIH-11538631 · Data updated 2026-11-12
A clinical trial in Zambia tests a new support program to help people with advanced HIV disease stay engaged in care after hospital discharge.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | July 1, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $245,124 |
| NIH project number | 3R01MH139390-01A1S1 |
| Project ID | NIH-11538631 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older with advanced HIV disease who have been hospitalized and are in or near Zambia.
✕Less likely to help
People without advanced HIV disease or those not recently hospitalized may not benefit from ARC.
What this research studies
If you have advanced HIV disease and recently left hospital, ARC provides a package of help from trained community health workers during your hospital stay and after you go home. The study will compare ARC to standard post-discharge care to see if it reduces deaths and improves HIV control and other health outcomes. It’s done as a randomized trial to measure how well the ARC approach works in real-world settings. The goal is to close gaps in care after hospitalization and prevent readmissions and complications.
Why it matters
Potential benefit: If successful, ARC could reduce mortality and improve health after hospital discharge for people with advanced HIV disease.
How similar studies have gone: Previous programs using community health workers have shown improvements in linkage to care, but this ARC intervention targets post-discharge outcomes in advanced HIV disease.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Vinikoor, Michael Jeffrey — University of Alabama at Birmingham
- Study coordinator: Vinikoor, Michael Jeffrey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.