Registry for older adults with blood cancers
Official title: Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry
Run by University of Alabama at Birmingham · NCT05556928 · Data updated 2026-11-12
This study is creating a registry for older adults with blood cancers to see how their health changes over time and to support future research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | July 21, 2020 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | December 8, 2025 |
| Trial ID | NCT05556928 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 50 and older with a biopsy-proven diagnosis of hematologic malignancies.
✕Probably not a fit
Patients younger than 50 years old or those who do not speak or read English may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to create a registry for older patients aged 50 and above who have been diagnosed with hematologic malignancies. Participants will undergo a geriatric assessment questionnaire and objective physical function testing, including the Short Physical Performance Battery and muscle strength assessment. The study will track changes in patient-reported outcomes over time through follow-up assessments at 3 months, 6 months, and one year. Additionally, a blood or saliva sample will be collected to support future research.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of frailty and geriatric impairments in older adults with blood cancers, leading to improved patient care.
How similar studies have gone: While this approach is focused on a specific population, similar registries have shown success in understanding geriatric conditions in cancer patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients are ≥50 years of age. * Patients have a biopsy proven diagnosis of Hematologic Malignancy (Multiple Myeloma, AL Amyloidosis, Waldenstrom's Macrogloblunemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic syndromes, Myeloproliferative Neoplasm, Acute/Chronic Myeloid Leukemia, Acute/Chronic Lymphoid Leukemia). * Patients have appointments at UAB including if they are an inpatient or other clinic locations. Exclusion Criteria: * Individuals who are \<50 years old. * Patients who do not read and/or speak English will not be eligible for this study as many of the questionnaires are not validated in other languages. No exclusions will be made based on gender, ethnicity or race.
Where it's running
-
Kirklin Clinic of UAB Hospital
Birmingham, Alabama, United States Recruiting
Study contacts
- Study coordinator: Landon Martin, BS
- Email: landoncmartin@uabmc.edu
- Phone: (205) 638-2120
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.