Clinical trial Recruiting at 1 site Observational Ages 50 and up

Registry for older adults with blood cancers

Official title: Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry

Run by University of Alabama at Birmingham · NCT05556928 · Data updated 2026-11-12

This study is creating a registry for older adults with blood cancers to see how their health changes over time and to support future research.

Quick facts

Study typeObservational
Ages50 Years and up
SexAll
Enrollment5000 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedJuly 21, 2020
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedDecember 8, 2025
Trial IDNCT05556928 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 50 and older with a biopsy-proven diagnosis of hematologic malignancies.

Probably not a fit

Patients younger than 50 years old or those who do not speak or read English may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to create a registry for older patients aged 50 and above who have been diagnosed with hematologic malignancies. Participants will undergo a geriatric assessment questionnaire and objective physical function testing, including the Short Physical Performance Battery and muscle strength assessment. The study will track changes in patient-reported outcomes over time through follow-up assessments at 3 months, 6 months, and one year. Additionally, a blood or saliva sample will be collected to support future research.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of frailty and geriatric impairments in older adults with blood cancers, leading to improved patient care.

How similar studies have gone: While this approach is focused on a specific population, similar registries have shown success in understanding geriatric conditions in cancer patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients are ≥50 years of age.
* Patients have a biopsy proven diagnosis of Hematologic Malignancy (Multiple Myeloma, AL Amyloidosis, Waldenstrom's Macrogloblunemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic syndromes, Myeloproliferative Neoplasm, Acute/Chronic Myeloid Leukemia, Acute/Chronic Lymphoid Leukemia).
* Patients have appointments at UAB including if they are an inpatient or other clinic locations.

Exclusion Criteria:

* Individuals who are \<50 years old.
* Patients who do not read and/or speak English will not be eligible for this study as many of the questionnaires are not validated in other languages. No exclusions will be made based on gender, ethnicity or race.

Where it's running

  • Kirklin Clinic of UAB Hospital
    Birmingham, Alabama, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.