Inspire HER: a heart-health and stress-support program for Black women
Inspire HER: Inspiring the Heart and Emotions for Radical Health
This project will test whether the Inspire HER lifestyle program helps Black women with higher heart disease risk improve heart health and manage stress.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 30 Years to 79 Years |
| Sex | Female |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Trial ID | NCT06966258 on ClinicalTrials.gov |
What this trial studies
Inspire HER is a 24-week lifestyle program adapted from Black Impact that combines regular physical activity, nutrition education, and connections to health coaches and community health workers. The team will refine the program using prior feedback and run a randomized, wait-list–controlled trial comparing Inspire HER to usual care among Black women with elevated cardiovascular-kidney-metabolic risk. The study will measure changes in heart-health metrics and biological responses to stress as primary outcomes, and will track self-reported stress, perceived health control, and unmet social needs as secondary outcomes. Investigators will also compare women's responses to existing Black Impact data in men to explore sex differences in stress and heart-health pathways.
Who should consider this trial
Good fit: Ideal candidates are English-speaking Black women aged 30–79 who live in the metropolitan Birmingham, Alabama area and have stage 2 or greater cardiovascular-kidney-metabolic syndrome with no provider-imposed limits on physical activity.
Not a fit: People who are not Black women, live outside the Birmingham area, have provider-imposed limits on physical activity, or do not have elevated cardiometabolic risk are unlikely to benefit from participating.
Why it matters
Potential benefit: If successful, Inspire HER could lower cardiovascular risk and improve stress-related health and access to social supports for Black women.
How similar studies have performed: A similar program (Black Impact) showed promising improvements in heart health and stress-related outcomes in Black men in earlier studies, and a larger Black Impact trial is ongoing.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Black women (self-report) * Adult ages 30-79 years * Stage 2 or greater Cardiovascular-Kidney-Metabolic Syndrome * English speaking * Lives in Metropolitan Birmingham, AL area. Exclusion Criteria: \- Healthcare provider-imposed physical activity limitations.
Where this trial is running
Birmingham, Alabama
- University of Alabama at Birmingham — Birmingham, Alabama, United States (Recruiting)
Study contacts
- Principal investigator: Timiya S Nolan, PhD — University to Alabama at Birmingha
- Study coordinator: LeAndrea D Anderson
- Email: leandreaanderson@uabmc.edu
- Phone: 205-996-0089
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.