See if deep brain stimulation for Parkinson's changes thinking and movement and affects fall risk

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study investigates cognitive and motor changes after deep brain stimulation (DBS) implantation in Parkinson’s disease patients and explores how these changes may influence fall risk. DBS is used as part of standard care to manage motor symptoms when medication is insufficient. The study aims to identify potential mechanisms contributing to falls and to lay groundwork for interventions that address post-DBS fall risk. It will assess participants over a defined follow-up period to observe changes in axial motor symptoms, balance, and related factors. The approach focuses on causal factors rather than comparing DBS to other treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 30-80, patient has elected to undergo DBS surgery as part of routine care, cleared for deep brain stimulation surgery as part of routine care by the movement disorders committee. Refractory motor symptoms such as dyskinesias, wearing off, and/or motor fluctuations, causing significant disability, despite reasonable attempts at medical management, as determined by the consensus DBS committee, able to walk, Patient is available for follow-up over the length of the study

Exclusion Criteria: Patient's insurance will not cover the costs of surgery with investigational devices, Medical contraindications such as current uncontrolled hypertension, heart disease, coagulopathy, or other conditions contraindicating DBS surgery or stimulation, self-report of lack of clear levodopa response, requires a walker or wheelchair for mobility

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Where it's running

• UAB WHARF at Lakeshore
  Homewood, Alabama, United States Recruiting

Study contacts

• Study coordinator: Christopher Hurt, PhD
• Email: cphurt@uab.edu
• Phone: 2059345817

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Spinal Mobility, Rigidity, and Kinesiophobia in Parkinson's Disease with and without TMD

  This study tests whether people with Parkinson's disease who have Temporomandibular Disorders differ in spinal mobility, axial rigidity, and kinesiophobia from those without TMD.

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• A 12-Week Trial of Flexilev with the OraFID Device and App for Parkinson's

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• How physical activity might help people with Parkinson’s disease who have DBS-STN implants

  This study tests whether adding regular physical activity can help people with Parkinson’s who have DBS-STN stimulation by trying a structured physiotherapy approach alongside standard care.

  Recruiting Medical University of Warsaw · Warsaw · NCT07838636

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.