Early time-restricted eating for older adults with high blood pressure
Official title: The Effect of Early Time-Restricted Eating on Cardiometabolic Health and Circadian Rhythms in Hypertensive Older Adults With Habitual Prolonged Eating Window
Run by University of Alabama at Birmingham · NCT07135505 · Data updated 2026-11-12
This project will try early time-restricted eating in adults 60 and older with high blood pressure to see if a shorter, earlier daily eating window improves body rhythms and cardiovascular and metabolic health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | February 16, 2026 |
| Main results expected | December 30, 2027 |
| Study ends | July 31, 2028 |
| Registry record updated | June 22, 2026 |
| Trial ID | NCT07135505 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are men and women aged 60 or older with average office systolic BP ≥130 mmHg, a habitual eating window of ≥12 hours per day on most days, and stable health over the past two months.
✕Probably not a fit
People with diagnosed diabetes or on diabetes medications, recent major cardiac events, those already fasting >12 hours daily, those actively in weight-loss programs, or those unable to maintain a regular early wake/sleep schedule are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study enrolls adults aged 60 and older with average office systolic blood pressure ≥130 mmHg who currently eat for ≥12 hours per day. Participants will switch to an earlier, shortened daily eating window and be followed for changes in circadian (body) rhythms and cardiometabolic measures. Researchers will collect physiological measurements such as blood pressure and metabolic markers and monitor timing of eating and activity. The goal is to determine whether shifting eating earlier in the day produces measurable improvements in rhythm alignment and cardiometabolic health in this population.
Why it matters
Potential benefit: If successful, the approach could lower blood pressure and improve metabolic health and daily rhythm stability in older adults.
How similar studies have gone: Previous time-restricted eating studies in younger and mixed-age adults have reported improvements in some cardiometabolic markers, but evidence specifically in older adults with hypertension is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consent to participate in the study * Men and women ≥ 60 years old * Average office systolic BP ≥130 mmHg * Self-reported ≥12 hours eating period per day of at least 5 days/week * Stable health history over the past 2 months Exclusion Criteria: * Fasting \>12 hours per day * Actively trying to lose weight by participating in formal weight loss program or significantly restricting calorie intake * Have lost ≥ 10 pounds in last 3 months * Unable to wake up at a regular time between 6-8 am * Perform overnight shift work more than 1day/week on average * Resting heart rate of \>120 beats per minute, systolic blood pressure \> 180 mmHg and/or diastolic blood pressure of \> 100 mmHg * Have been diagnosed with diabetes * On insulin or diabetes medication * Unstable angina, heart attack or stroke in the past 3 months * Continuous use of supplemental oxygen to manage a chronic pulmonary condition or heart failure * Pregnant or breastfeeding * Rheumatoid arthritis, Parkinson's disease or currently on dialysis * Current diagnosis of a major psychiatric condition that would impair study participation * Severe gastrointestinal disease, major gastrointestinal surgery, or active gallstone disease * Active treatment for cancer in the past year * Taking medications that preclude fasting for 16 hours (e.g. must be taken with food at least 12 hours apart)
Where it's running
-
University of Alabama at Birmingham
Birmingham, Alabama, United States Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using low-dose aspirin after preeclampsia to improve recovery
This study is testing if taking low-dose aspirin for six months after having preeclampsia can help new moms recover better by improving their blood pressure and blood vessel function.
-
IMB-guided health education to boost medication taking and blood pressure control in adults with hypertension
This study tests a health-literacy program based on Information-Motivation-Behavioral Skills to help adults with hypertension who don’t take their medicines regularly to take them more consistently and better control their blood pressure.
-
Renal Nerve Stimulation to Help Blood Pressure in AF and HFpEF
This study tests whether stimulating the kidneys with a catheter can safely lower blood pressure in adults with atrial fibrillation and HFpEF who also have hypertension.
-
Hypertension: Does Education Help Patients Manage Blood Pressure Better?
This study tests whether structured patient education improves blood pressure control and self-management in adults with hypertension who speak Turkish.
-
High BMI and periodontitis in Thai adults under 60
This study tests how common high BMI and periodontitis are among Thai adults aged 18–59 and what factors are linked to them.
-
Long-term GW906 treatment for people with essential hypertension
This trial tests whether long-term GW906 injections are safe and effective for adults with essential hypertension who completed an earlier GW906 study.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.