How pneumococcal conjugate vaccines may produce antibodies that protect against serogroup 33.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this Phase 4, post-licensure comparison, healthy adult participants will receive one of two licensed pneumococcal conjugate vaccines and have blood drawn before and after vaccination. Laboratory assays will measure the presence and bactericidal activity of antibodies specifically against serogroup 33. Individuals with prior pneumococcal vaccination or conditions/medications that suppress immunity are excluded. The study is conducted at the University of Alabama at Birmingham in collaboration with Merck.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy adult

Exclusion Criteria:

* No prior history of pneumococcal vaccination
* No immunosuppressing medications or chronic diseases that affect immune function

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting

Study contacts

• Study coordinator: David LaFon, MD
• Email: dlafon@uabmc.edu
• Phone: 2059343411

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.